Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ic50 for monomerid = 50135800
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  0.710nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  0.710nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  0.710nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  0.710nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [33S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as DAMGO-stimulated [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes Pharma Ireland

US Patent
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity was determined in stimulating [35S]-GTP-gamma S binding mediated by the Opioid receptor mu 1 in chinese Hamster Ovary (CHO)membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed