Affinity DataIC50: >1.60E+3nMAssay Description:Inhibition of tyrosinase (unknown origin) assessed as reduction in melanin formationMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of tyrosinase in Melan-a cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.75E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F1 cellsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.01E+5nMAssay Description:Inhibition of mushroom tyrosinase after 25 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibition of mushroom tyrosinase after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+5nMpH: 6.8 T: 2°CAssay Description:Briefly, mushroom tyrosinase (1250 units/mL) and 2 mM L-tyrosine (0.07 mL) were added to a solution of phosphate buffer (0.1 M, pH 6.8, 0.09 mL) cont...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.66E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins by photom...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.60E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as reduction in dopachrome production after 20 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+6nMAssay Description:Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrateMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.30E+6nMAssay Description:Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+6nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+6nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+6nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.30E+6nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.30E+6nMAssay Description:Inhibition of mushroom tyrosinase assessed as 3,4-dihydroxy-L-phenylalanine oxidationMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.04E+7nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.04E+7nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.04E+7nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.40E+7nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Seoul National University Of Science And Technology
Curated by ChEMBL
Seoul National University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.40E+7nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+7nMAssay Description:Inhibitory activity against mushroom tyrosinaseMore data for this Ligand-Target Pair