BindingDB PrimarySearch_ki

Found 33 of ic50 for monomerid = 50346918

Mitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: 12nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Mitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: 17nMAssay Description:Inhibition of p38alpha kinase in human monocytesMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Mitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: 249nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Mitogen-activated protein kinase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Mitogen-activated protein kinase 10(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Mitogen-activated protein kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Dual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MKK6More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Cyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Inhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Aurora kinase A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of AURKAMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of TBK1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Tyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Casein kinase I isoform alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of CK1More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Serine/threonine-protein kinase Chk2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Tyrosine-protein kinase Lyn(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

MAP kinase-activated protein kinase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MK3More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Mitogen-activated protein kinase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Dual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MKK4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Serine/threonine-protein kinase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MST2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Tyrosine-protein kinase SYK(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Angiopoietin-1 receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Dual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MKK7More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Tyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of ZAP70More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of MYT1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Serine/threonine-protein kinase PLK3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Inhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Rho-associated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of ROCK IIMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Mitogen-activated protein kinase 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

ALK tyrosine kinase receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

PNG

BDBM50346918(CHEMBL1738710)

IC50: >1.00E+4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed

Filter my 33 hits

Targets 32▿
- Mitogen-activated protein kinase 14 2
- Mitogen-activated protein kinase 1 1
- Serine/threonine-protein kinase 3 1
- Mitogen-activated protein kinase 3 1
- Tyrosine-protein kinase BTK 1
- Mitogen-activated protein kinase 9 1
- Epidermal growth factor receptor 1
- Mitogen-activated protein kinase 8 1
- Tyrosine-protein kinase SYK 1
- Angiopoietin-1 receptor 1
- Serine/threonine-protein kinase TBK1 1
- ALK tyrosine kinase receptor 1
- Aurora kinase A 1
- Receptor-type tyrosine-protein kinase FLT3 1
- Inhibitor of nuclear factor kappa-B kinase subunit beta 1
- Serine/threonine-protein kinase PLK3 1
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 1
- Mitogen-activated protein kinase 11 1
- Mitogen-activated protein kinase 10 1
- Casein kinase I isoform alpha 1
- Tyrosine-protein kinase Lyn 1
- Cyclin-dependent kinase 2 1
- Serine/threonine-protein kinase Chk2 1
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Dual specificity mitogen-activated protein kinase kinase 6 1
- Dual specificity mitogen-activated protein kinase kinase 7 1
- Dual specificity mitogen-activated protein kinase kinase 4 1
- Rho-associated protein kinase 2 1
- MAP kinase-activated protein kinase 2 1
- Tyrosine-protein kinase ZAP-70 1
- MAP kinase-activated protein kinase 3 1
Publications 1▿
- Bioorg Med Chem Lett 21: 3856-60 (2011) 33
Institutions 1▿
- Pfizer 33
Affinity: 12 to 1.0E+4 nM▿
- IC50 33
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 0