Compile Data Set for Download or QSAR
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Found 39 of ic50 for monomerid = 50391643
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged HER2 cytoplasmic domain amino acid 676 to 1255 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  11nMAssay Description:Inhibition of human N-terminal DYKDDDD tagged EGFR cytoplasmic domain amino acid 669 to 1210 expressed in baculovirus after 5 mins by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  160nMAssay Description:Inhibition of HER4 cytoplasmic domain after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  500nMAssay Description:Inhibition of N-terminal His6-tagged Aurora B expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  980nMAssay Description:Inhibition of N-terminal GST-tagged MEK1 after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of LCK after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of LYN B after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of LYN A after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of c-Met after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of CSK after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged GSK3beta expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1 after 5 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR3 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Src after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged MEKK expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged TTK expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF-1R after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged IKKbeta expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged ERK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length N-terminal FLAG-tagged FAK expressed in baculovirus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged ASK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged p38alpha expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of INSR after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TIE2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged PLK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged MEK5 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged JNK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-kit after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ZAP70 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged B-raf expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged TAK1 expressed in baculovirus after 5 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR1 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged VEGFR2 cytoplasmic domain expressed in baculovirus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRbeta after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDGFRalpha after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391643(CHEMBL2148052 | CHEMBL2148053)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length N-terminal FLAG-tagged BMX expressed in baculovirus after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed