Compile Data Set for Download or QSAR
maximum 50k data
Found 34 of ic50 for monomerid = 50429477
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  1nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of Erk1/2 phosphorylation after 20 hrs by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cells after 20 hrs by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  3nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of STAT5 phosphorylation after 20 hrs by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  12nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed by baculovirus in Sf21 insect cells measured after 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  39nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  72nMAssay Description:Inhibition of c-RAF (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  223nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  408nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  507nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Danio rerio)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Pim-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CAMK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMegakaryocyte-associated tyrosine-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERN1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyotonin-protein kinase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50429477(CHEMBL2332840)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CHEK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed