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Found 34 of ic50 for monomerid = 50544440
TargetTriple specificity protein phosphatase PtpB()
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  6.40nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTriple specificity protein phosphatase PtpB()
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis H37Rv MptpB using pNPP as substrate incubated for 10 mins and measured by spectrophotometric met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  25nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB I203A mutant expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  91nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB I207A mutant expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  374nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB I207K mutant expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB F161S mutant expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase eta(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of DEP1 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLaforin(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Laforin (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 6(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTP-PEST (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CD45 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of STEP (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of VHR (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target6-pyruvoyl tetrahydrobiopterin synthase(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPS (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2A activator(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPA (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPB (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPM (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPG (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPE (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Compounds were tested against mPTPB using the p-nitrophenyl phosphate (pNPP) assay system in a Cary 100 UV-Vis spectrophotometer by monitoring the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of FAP1 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HePTP (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of LYP (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TCPTP (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of SHP1 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of SHP2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed