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Found 3 of ec50 for monomerid = 5447
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataEC50:  2.16E+3nMAssay Description:Inhibition of wild-type EGFR in human A431 cells assessed as reduction in cell viability after 96 hrs by CellTiterGlo assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataEC50:  300nMAssay Description:Inhibition of BCRP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of P-gp (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed