TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Mrc
Mrc
Affinity DataIC50: 3.80E+3nM Kd: 280nMpH: 7.2 T: 2°CAssay Description:Binding was detected as a change in the intrinsic tryptophan fluorescence of the PI3K upon the addition of inhibitor. The inhibitor was incubated wit...More data for this Ligand-Target Pair
TargetIsoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A) 68-320](Homo sapiens (Human))
National Taiwan University
National Taiwan University
Affinity DataKd: 1.70E+3nMpH: 4.0Assay Description:Recombinant full-length hnRNPA1 (aa 1-320) and truncated versions of hnRNPA1, including the N-terminal RNA binding domain (aa 1-196), the middle regi...More data for this Ligand-Target Pair
Affinity DataKd: 38.7nMAssay Description:Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysisMore data for this Ligand-Target Pair
Affinity DataKd: 5.18E+4nMAssay Description:Binding affinity to human MMP-1 catalytic domain (100 to 269 residues) expressed in Escherichia coli BL21 Star (DE3) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 7.08E+3nMAssay Description:Binding affinity to ABCB1 nucleotide binding domain 2More data for this Ligand-Target Pair
Affinity DataKd: 1.29E+4nMAssay Description:Binding affinity to Helicobacter pylori Ddl by surface plasmon resonance biosensor technologyMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
National Research Council (Itb-Cnr)
Curated by ChEMBL
National Research Council (Itb-Cnr)
Curated by ChEMBL
Affinity DataKd: 2.56E+4nMAssay Description:Binding affinity to sensorchip-immobilized human His-tagged CFTR F508 deletion mutant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetIsoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A)(Homo sapiens (Human))
National Taiwan University
National Taiwan University
Affinity DataKd: 8.90E+3nMpH: 4.0Assay Description:Recombinant full-length hnRNPA1 (aa 1-320) and truncated versions of hnRNPA1, including the N-terminal RNA binding domain (aa 1-196), the middle regi...More data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to non phosphorylated PIM1More data for this Ligand-Target Pair