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Found 2 of ic50 for UniProtKB: A0A0B4ZMU3
TargetDihydrofolate reductase(Streptococcus pneumoniae (ATCC49619))
Arpida

LigandPNGBDBM18071(5-chloro-3-({4-[(2,4-diaminopyrimidin-5-yl)methyl]...)
Affinity DataKi:  9nM ΔG°:  -11.2kcal/mole IC50:  90nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
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TargetDihydrofolate reductase(Streptococcus pneumoniae (ATCC49619))
Arpida

LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  5.60E+3nM ΔG°:  -7.28kcal/mole IC50:  4.20E+4nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In DepthDetails