Affinity DataIC50: 3.00E+4nM Kd: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:A tritium release assay was used to determin the in vitro inhibitory strengths of various compounds. The inhibitory potency of human TS was determin...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nM Kd: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:A tritium release assay was used to determin the in vitro inhibitory strengths of various compounds. The inhibitory potency of human TS was determin...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nM Kd: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:A tritium release assay was used to determin the in vitro inhibitory strengths of various compounds. The inhibitory potency of human TS was determin...More data for this Ligand-Target Pair
Affinity DataKd: 4.40E+4nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Compound was evaluated for average apparent binding constant (Kd ) using Scatchard analysis to dTMP synthetase enzyme from chick embryoMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 1.20E+5nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
Affinity DataKd: 2.50E+4nMAssay Description:Binding affinity to thymidylate synthetase (unknown origin)More data for this Ligand-Target Pair
