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Found 17 of ec50 for UniProtKB: P41144
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384053(CHEMBL2032453)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384059(CHEMBL2032452)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50384054(CHEMBL2032447)
Affinity DataEC50:  0.220nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig illeum assessed as electric field-stimulated responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595849(CHEMBL5169404)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595853(CHEMBL5177451)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM224024(BDBM50241435 | Dynorphin A (1-13) | YGGFLRRXRPKLK)
Affinity DataEC50:  18nMAssay Description:Binding affinity towards k-opioid receptor k-EL-2 mutant (wild-type) expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354578(BUPRENORPHINE | US10752592, Compound buprenorphine...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at KOR in guinea pig vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595847(CHEMBL5199097)
Affinity DataEC50:  22nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595846(CHEMBL5183917)
Affinity DataEC50:  26nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  53nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50474152(CHEBI:6956 | CHEMBL299031)
Affinity DataEC50:  230nMAssay Description:Agonist activity at kappa opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595851(CHEMBL5192735)
Affinity DataEC50:  955nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595848(CHEMBL5179970)
Affinity DataEC50:  1.35E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21130(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at kappa opioid receptor guinea pig colon tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595852(CHEMBL5194818)
Affinity DataEC50:  1.86E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50595850(CHEMBL5188021)
Affinity DataEC50:  9.55E+3nMAssay Description:Agonist activity at KOR in guinea pig brain membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed