TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.0570nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.230nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.280nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.310nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.330nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.450nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.460nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.720nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.720nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.10nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at human TGR5More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 2.90nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3.10nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3.30nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as cAMP level after 48 hrs by fluorescent assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3.90nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as cAMP level after 48 hrs by fluorescent assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3.98nMAssay Description:Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 3.98nMAssay Description:Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Zydus Research Centre
Curated by ChEMBL
Zydus Research Centre
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair