Compile Data Set for Download or QSAR
maximum 50k data
Found 311 of ec50 for UniProtKB: P14902
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168435(US9675571, 129)
Affinity DataEC50:  0.5nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168360(US9675571, 34)
Affinity DataEC50:  2nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168315(US9675571, ent-1J)
Affinity DataEC50:  2nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168358(US9675571, 31)
Affinity DataEC50:  4nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168337(US9675571, 30)
Affinity DataEC50:  6nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168378(US9675571, 37)
Affinity DataEC50:  7nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168377(US9675571, 36)
Affinity DataEC50:  7nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataEC50:  8nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168314(US9675571, 1J)
Affinity DataEC50:  8nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataEC50:  8.70nMAssay Description:Inhibition of human IDO1 expressed in HEK293 cells assessed as reduction in kynurenine production after 30 minsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50046104(CHEMBL3310297)
Affinity DataEC50: >10nMAssay Description:Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545137(CHEMBL4644903 | US11591301, Compound 1)
Affinity DataEC50:  11nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataEC50:  13nMAssay Description:Inhibition of IFNgamma-stimulated IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526970(5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin 7-...)
Affinity DataEC50:  13nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526969(5-(1-(2,3-difluorophenyl)imidazo[1,5-a]pyridin-5- ...)
Affinity DataEC50:  15nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526968(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  15nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545146(CHEMBL4639448 | US11591301, Compound 21)
Affinity DataEC50:  15nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545138(CHEMBL4645780 | US11591301, Compound 15)
Affinity DataEC50:  17nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526967(5-(3-chloro-1-(2,3-difluorophenyl)imidazo[1,5- a]p...)
Affinity DataEC50:  19nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545147(CHEMBL4642406)
Affinity DataEC50:  20nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526966(N-(4-fluorophenyl)-5-(3-(pyridin-3- yl)imidazo[1,2...)
Affinity DataEC50:  21nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168399(US9675571, 60)
Affinity DataEC50:  21nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168413(US9675571, 67)
Affinity DataEC50:  23nMT: 2°CAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526965(5-(3-(2,3-difluorophenyl)imidazo[1,2- b]pyridazin-...)
Affinity DataEC50:  25nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545148(CHEMBL4637369)
Affinity DataEC50:  27nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584087(CHEMBL5093619)
Affinity DataEC50:  30nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50145159(CHEMBL3765205)
Affinity DataEC50:  31nMAssay Description:Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584085(CHEMBL5074542)
Affinity DataEC50:  33nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545142(CHEMBL4646789)
Affinity DataEC50:  33nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50145160(CHEMBL3764846)
Affinity DataEC50:  36nMAssay Description:Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526964(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  37nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526963(5-(3-(2,3-difluorophenyl)-2- (hydroxymethyl)imidaz...)
Affinity DataEC50:  40nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584084(CHEMBL5080101)
Affinity DataEC50:  40nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545140(CHEMBL4644666 | US11591301, Compound 3)
Affinity DataEC50:  41nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526962(5-(3-(2,3-difluorophenyl)imidazo[1,2-a]pyridin-8- ...)
Affinity DataEC50:  45nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50203249(CHEMBL3945146)
Affinity DataEC50:  48nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584073(CHEMBL5081219)
Affinity DataEC50:  48nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50203269(CHEMBL3913434)
Affinity DataEC50:  52nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50203281(CHEMBL3971895)
Affinity DataEC50:  52nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545136(CHEMBL4639516)
Affinity DataEC50:  53nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584076(CHEMBL5083059)
Affinity DataEC50:  54nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50138819(CHEMBL3753837 | US10233190, Example 1357)
Affinity DataEC50:  55nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells incubated for 24 hrsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526961(N-(4-fluorophenyl)-5-(3-(5-fluoropyridin-3- yl)imi...)
Affinity DataEC50:  58nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM370526(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)
Affinity DataEC50:  59nMAssay Description:Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM526960(N-(4-fluorophenyl)-5-(3-(pyridin-3- yl)imidazo[1,2...)
Affinity DataEC50:  59nMAssay Description:To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584082(CHEMBL5094486)
Affinity DataEC50:  59nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50545135(CHEMBL4645599)
Affinity DataEC50:  59nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50300305(4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2...)
Affinity DataEC50:  59nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50584075(CHEMBL5076745)
Affinity DataEC50:  60nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)
Affinity DataEC50:  61nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells incubated for 24 hrsMore data for this Ligand-Target Pair
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