Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human IP expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of cA...More data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Agonist activity at human IP expressed in HEK293 cells assessed as increase in cAMP level incubated for 20 mins measured after 60 mins addition of cA...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Principle of the assay: The HTRF® assay kit was purchased from Cisbio-US, Inc. (Bedford, Mass.; Catalog #62AM4PEC). The HTRF® assay supported by the ...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.14nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.60nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Principle of the assay: The HTRF® assay kit was purchased from Cisbio-US, Inc. (Bedford, Mass.; Catalog #62AM4PEC). The HTRF® assay supported by the ...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Affinity DataEC50: 7.80nMAssay Description:Affinity to delta opioid receptor determined in the presence of [3H]- [D-Pen2,5]enkephalin using membranes prepared from rat cerebrumMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:The HTRF® assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volum...More data for this Ligand-Target Pair
Affinity DataEC50: 8.5nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.5nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 8.70nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 9.5nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Principle of the assay: The HTRF® assay kit was purchased from Cisbio-US, Inc. (Bedford, Mass.; Catalog #62AM4PEC). The HTRF® assay supported by the ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Principle of the assay: The HTRF® assay kit was purchased from Cisbio-US, Inc. (Bedford, Mass.; Catalog #62AM4PEC). The HTRF® assay supported by the ...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Affinity DataIC50: 476nM EC50: 16nMpH: 7.4 T: 2°CAssay Description:IP receptor binding activity was quantified via a filter binding assay measuring displacement of [3H]-Iloprost binding to human platelet membranes. R...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 19.1nMAssay Description:Compounds were screened for agonists of the human prostacyclin (PGI2) receptor using the HTRF assay for direct cAMP measurement (Gabriel et al., ASSA...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at recombinant human IP receptor expressed in CHO-K1 cells assessed as increase in intracellular cAMP level after 1 hr incubation by...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level by HTRF methodMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:The HTRF® assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volum...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:The HTRF® assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volum...More data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 37nMAssay Description:Agonist activity at human recombinant IP receptor expressed in CHO-K1 cells incubated for 1 hr by HTRF cAMP assayMore data for this Ligand-Target Pair