Compile Data Set for Download or QSAR
Found 4 of kd for UniProtKB: P20272
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50356013(CHEMBL1911374 | CHEMBL1911375)
Show SMILES FC(F)(F)c1ccc(Cn2nc3c(-c4ccncc4)c(cnn3c2=O)-c2ccc(Cl)cc2)cn1
Show InChI InChI=1S/C23H14ClF3N6O/c24-17-4-2-15(3-5-17)18-12-30-33-21(20(18)16-7-9-28-10-8-16)31-32(22(33)34)13-14-1-6-19(29-11-14)23(25,26)27/h1-12H,13H2
Affinity DataKd:  29.1nMAssay Description:Binding affinity to rat brain CB1 receptor after 90 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre of the Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Show SMILES CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
Affinity DataKd:  6.5nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes assessed as dissociation rate constant at 10 uM by liquid scintillation anal...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre of the Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Show SMILES CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Show InChI InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
Affinity DataKd:  3.40nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes assessed as dissociation constant by liquid scintillation analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50356013(CHEMBL1911374 | CHEMBL1911375)
Show SMILES FC(F)(F)c1ccc(Cn2nc3c(-c4ccncc4)c(cnn3c2=O)-c2ccc(Cl)cc2)cn1
Show InChI InChI=1S/C23H14ClF3N6O/c24-17-4-2-15(3-5-17)18-12-30-33-21(20(18)16-7-9-28-10-8-16)31-32(22(33)34)13-14-1-6-19(29-11-14)23(25,26)27/h1-12H,13H2
Affinity DataKd:  12.4nMAssay Description:Displacement of [3H]-SR-141716 from rat CB1 receptorMore data for this Ligand-Target Pair