Compile Data Set for Download or QSAR
maximum 50k data
Found 1123 of ki for UniProtKB: P37288
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50221813(CHEMBL394602 | HO-LVA)
Affinity DataKi:  0.0320nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in CHO cells by polarisation binding assay using 384-well plate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50221813(CHEMBL394602 | HO-LVA)
Affinity DataKi:  0.0360nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in CHO cells by polarisation binding assay using 96-well plate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418929(CHEMBL1807272)
Affinity DataKi:  0.0372nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418907(CHEMBL1807267)
Affinity DataKi:  0.0398nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50319772((2'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-trimethyl-6...)
Affinity DataKi:  0.0500nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50319776((2,2'-dimethylbiphenyl-4-yl)((1S,5R)-1,3,3-trimeth...)
Affinity DataKi:  0.0600nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM593676(2'-(3-hydroxy-7,7-dimethyl-1'H,7H- spiro[furo[3,4-...)
Affinity DataKi:  0.0630nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50075724(4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(5C-...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50075720((HO-LVA23)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-4-H...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50221815(4-({[(6-{N-[(1S)-5-amino-1-carbamoylpentyl]-1-[(3S...)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]AVP from human vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418909(CHEMBL1807270)
Affinity DataKi:  0.0955nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50319799((4-(1H-indol-3-yl)-3-methoxyphenyl)((1S,5R)-1,3,3-...)
Affinity DataKi:  0.100nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50075725(4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(6C-...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50075722(4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(5C-...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418906(CHEMBL1807266)
Affinity DataKi:  0.182nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50114031((2S)-1-[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-(3,4...)
Affinity DataKi:  0.190nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 96-well plate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50202918((S)-N-(2-fluoro-3-(trifluoromethyl)benzyl)-5-(4-cy...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM593614(5-hydroxy-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  0.200nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50469544(CHEMBL4281963)
Affinity DataKi:  0.200nMAssay Description:Displacement of [Se-Se]-AVP from human V1A receptor expressed in CHO cells after 4 hrs by RP-LC-ICPMS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418914(CHEMBL1807281)
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418914(CHEMBL1807281)
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50221813(CHEMBL394602 | HO-LVA)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 384-well plate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50221813(CHEMBL394602 | HO-LVA)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 96-well plate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50075728(4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(6C-...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [125I]- HO-LVA from human Vasopressin V1a receptor in membranes of CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418366(CHEMBL1774023)
Affinity DataKi:  0.234nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418366(CHEMBL1774023)
Affinity DataKi:  0.234nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418905(CHEMBL1807273)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418910(CHEMBL1807271)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50202900((S)-N-(3-(trifluoromethyl)benzyl)-5-(4-cyclohexylp...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50221813(CHEMBL394602 | HO-LVA)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human vasopressin V1a receptor expressed in COS7 cells by HTRF-FRET assay using 96-well plate cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50583877(CHEMBL5070261)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-arginine-vasopressin from human V1A receptor expressed in human 1321N1 cell membranes incubated for 60 mins by radioligand bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50583879(CHEMBL5070075)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-arginine-vasopressin from human V1A receptor expressed in human 1321N1 cell membranes incubated for 60 mins by radioligand bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50202920(2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylme...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50583878(CHEMBL5074709)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-arginine-vasopressin from human V1A receptor expressed in human 1321N1 cell membranes incubated for 60 mins by radioligand bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50459408(CHEMBL3307200)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-AVP from human V1A receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50319774((3-chloro-2'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-tr...)
Affinity DataKi:  0.310nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM593606(2'-(1'H,3H-spiro[2-benzofuran-1,4'- piperidin]-1'-...)
Affinity DataKi:  0.316nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50319788(CHEMBL1084325 | N-(2'-methoxy-4'-((1S,5R)-1,3,3-tr...)
Affinity DataKi:  0.370nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418930(CHEMBL1807278)
Affinity DataKi:  0.372nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50418930(CHEMBL1807278)
Affinity DataKi:  0.372nMAssay Description:Displacement of [3H]AVP from human V1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50202882((S)-N-(2,3-dichlorobenzyl)-5-(4-cyclohexylpiperazi...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM288715(US10092551, Example 23)
Affinity DataKi:  0.398nM ΔG°:  -12.8kcal/moleT: 2°CAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM288741(US10092551, Example 49 | US10092551, Example 96)
Affinity DataKi:  0.398nM ΔG°:  -12.8kcal/moleT: 2°CAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM593639(5,6-difluoro-2'-(1'H,3H-spiro[2- benzofuran-1,4'-p...)
Affinity DataKi:  0.398nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50583881(CHEMBL5081323)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-arginine-vasopressin from human V1A receptor expressed in human 1321N1 cell membranes incubated for 60 mins by radioligand bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50469541(CHEMBL4289837)
Affinity DataKi:  0.400nMAssay Description:Displacement of [Se-Se]-AVP from human V1A receptor expressed in CHO cells after 4 hrs by RP-LC-ICPMS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50202902((S)-N-(2-fluoro-5-(trifluoromethyl)benzyl)-5-(4-cy...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM85095(CAS_151171 | CONIVAPTAN | NSC_151171 | YM087)
Affinity DataKi:  0.430nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50546431(CHEMBL4759005)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in 1132N1 cells assessed as dissociation constant by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Institute Genomics Functional (Igf)

Curated by ChEMBL
LigandPNGBDBM50202873((S)-N-(3-(trifluoromethyl)benzyl)-5-(4-(cyclohexyl...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity for human cloned vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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