Affinity DataEC50: 0.00280nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as induction of [3H]thymidine incorporation after 2 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0560nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in HEK293 cells co-expressing Galphao1 assessed as incorporation of [35S]GTPgammaS into Galp...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0600nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0800nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0850nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0850nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.110nMAssay Description:Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation prein...More data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at RLuc8-fused Go-coupled human D3R expressed in HEK293 cells untagged beta1 and mVenus-tagged gamma2 measured after 5 mins in prese...More data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Intrinsic activity against dopamine D3 receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.25nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.260nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.320nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 0.324nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 0.330nMAssay Description:Agonist activity at human D3 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.330nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.360nMAssay Description:Intrinsic activity in mitogenesis assay using Dopamine receptor D3 expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.420nMAssay Description:Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation prein...More data for this Ligand-Target Pair
Affinity DataEC50: 0.427nMAssay Description:Inhibitory concentration of compound against LPS- induced TNF-alpha production in whole human blood assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.430nMAssay Description:Inhibitory concentration of compound against LPS- induced TNF-alpha production in whole human blood assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.479nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 0.480nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 0.493nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.520nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.528nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.530nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTP gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.531nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.560nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.630nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTP gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.690nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.730nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
Affinity DataEC50: 0.740nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.780nMAssay Description:Agonist activity at human D3 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.810nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
Affinity DataEC50: 0.820nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.840nMAssay Description:Agonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.870nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at recombinant human dopamine D3 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at recombinant human dopamine D3 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 30 mins by HTRF ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.940nMAssay Description:Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTP gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.950nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.950nMAssay Description:Agonist activity at dopamine D3 receptor in human U2OS-D3 cells assessed as EA-tagged beta-arrestin translocation after 1.5 hrs by luminescence based...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Partial agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as inhibition of cAMP accumulation by flourescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human recombinant dopamine D3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair