Compile Data Set for Download or QSAR
maximum 50k data
Found 155 of ki for UniProtKB: P30940
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataKi:  2nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  2nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
Affinity DataKi:  2nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1 receptor was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026968(9-Chloro-11-(1-methyl-piperidin-4-ylidene)-11H-ben...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026974(9-Bromo-11-(1-methyl-piperidin-4-ylidene)-6,11-dih...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026970(9-Chloro-11-(1-methyl-piperidin-4-ylidene)-6,11-di...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026964(9-Bromo-11-(1-methyl-piperidin-4-ylidene)-11H-benz...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026971(11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026972(11-(1-Methyl-piperidin-4-ylidene)-11H-benzo[d]pyrr...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(RAT)
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50031942((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
Affinity DataKi:  13.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026963(11-(1-Methyl-piperidin-4-ylidene)-6,11-dihydro-5H-...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017453(1-(2-Ethyl-phenyl)-piperazine | CHEMBL9467)
Affinity DataKi:  17nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026973(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001855(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  18nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017448(1-(2-Isopropoxy-phenyl)-piperazine | CHEMBL9669)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017460(1-(2-Butoxy-phenyl)-piperazine | CHEMBL9452)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30704((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Affinity DataKi:  20nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)
Affinity DataKi:  20nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50007406(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)
Affinity DataKi:  20nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017450(1-(2-Isopropyl-phenyl)-piperazine | CHEMBL276156)
Affinity DataKi:  23nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026967(11-(1-Methyl-piperidin-4-ylidene)-9-trifluoromethy...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001901(1-(2-Chloro-phenyl)-piperazine | CHEMBL9841)
Affinity DataKi:  24nMAssay Description:Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Affinity DataKi:  25nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50026969(11-(1-Methyl-piperidin-4-ylidene)-6,11-dihydro-5H-...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]LSD radioligand binding at the serotonin-1 binding site of rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017458(2-Piperazin-1-yl-benzonitrile | CHEMBL275943)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001874(1-{5-[4-(2-Ethyl-phenyl)-piperazin-1-ylmethyl]-1-m...)
Affinity DataKi:  27nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001862((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Affinity DataKi:  28nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001862((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Affinity DataKi:  29nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001889(1-{5-[4-(2-sec-Butoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  29nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001861(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  33nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017451(1-(2-Propyl-phenyl)-piperazine | CHEMBL9870)
Affinity DataKi:  35nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001860(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  41nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001858(1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]...)
Affinity DataKi:  41nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017454(1-(2-Ethoxy-phenyl)-piperazine | CHEMBL273923)
Affinity DataKi:  43nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30707(2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...)
Affinity DataKi:  50nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001856(1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]...)
Affinity DataKi:  50nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(RAT)
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50027065((5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)e...)
Affinity DataKi:  52.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001869(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  57nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017457(1-(2-Fluoro-phenyl)-piperazine | CHEMBL9429)
Affinity DataKi:  58nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001863(1-{5-[4-(2-Butoxy-phenyl)-piperazin-1-ylmethyl]-1-...)
Affinity DataKi:  59nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001903(1-o-Tolyl-piperazine | CHEMBL9746)
Affinity DataKi:  62nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(RAT)
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50005835((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)
Affinity DataKi:  64.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017459(1-(2-Butyl-phenyl)-piperazine | CHEMBL9921)
Affinity DataKi:  65nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(RAT)
University Of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  67.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001876(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  69nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001866(1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]...)
Affinity DataKi:  76nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001870(1-{5-[4-(2-Ethoxy-phenyl)-piperazin-1-ylmethyl]-1-...)
Affinity DataKi:  76nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001879(1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]...)
Affinity DataKi:  82nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017455(1-(3-Fluoro-phenyl)-piperazine | CHEMBL269784)
Affinity DataKi:  87nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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