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Found 58 of ic50 for UniProtKB: Q63634
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268532(3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzo...)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50268739(CHEMBL524085 | N-(3-(4-chlorophenyl)isoxazol-5-yl)...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50089038(CGP 71683 | CGP-71683A | CHEMBL17645 | N-{[(1r,4r)...)
Affinity DataIC50:  1.40nMAssay Description:Compound was tested for rat Neuropeptide Y receptor type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50304297(CHEMBL594163 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249869(3-oxo-N-(5-phenylpyrazin-2-yl)-3H-spiro[isobenzofu...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I]PYY from rat NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50304301(CHEMBL595790 | trans-N-[1-(3-Fluorophenyl)-1H-pyra...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50304300(CHEMBL595573 | trans-N-[1-(2-fluorophenyl)-3-pyraz...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50304299(CHEMBL595560 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50073051(CHEMBL60319 | N-[5-(3,4-Dimethoxy-phenyl)-1H-pyraz...)
Affinity DataIC50:  2.30nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50304302(3'-oxo-N-(5-phenylpyrazin-2-yl)-3'H-spiro[cyclohex...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50145232(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)
Affinity DataIC50:  2.90nMAssay Description:In vitro binding affinity of the compound against rat neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50073055(2-Methyl-4-pyrrolidin-1-yl-6-[(E)-2-(3-trifluorome...)
Affinity DataIC50:  4.10nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50304298(CHEMBL595120 | trans-3-Oxo-N-(1-phenyl-1H-pyrazol-...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50145236(1-{4-[(9-Fluoro-4,5-dihydro-6-oxa-3-thia-1-aza-ben...)
Affinity DataIC50:  6nMAssay Description:In vitro binding affinity of the compound against rat neuropeptide Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50116600(CHEMBL325475 | N-(9-Ethyl-9H-carbazol-3-yl)-3-pyri...)
Affinity DataIC50:  7nMAssay Description:Binding affinity against rat Neuropeptide Y receptor Y5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163525(CHEMBL179972 | N-(4-Benzoyl-phenyl)-2-[4-(2-oxo-4H...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163516(2-[4-(6-Fluoro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163541(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50073047(CHEMBL291666 | N-[5-(3,4-Dimethoxy-phenyl)-1H-pyra...)
Affinity DataIC50:  8.30nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163539(CHEMBL557802 | N-(9-Hydroxy-9H-fluoren-3-yl)-2-[4-...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163552(CHEMBL557540 | N-(9-Methyl-9H-carbazol-3-yl)-2-[4-...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163513(CHEMBL541121 | N-(4-Benzoyl-phenyl)-2-[4-(6-chloro...)
Affinity DataIC50:  11.2nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163545(CHEMBL537412 | N-(4-Acetyl-phenyl)-2-[4-(2-oxo-4H-...)
Affinity DataIC50:  17.3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163535(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163526(CHEMBL537191 | N-(4-Acetyl-phenyl)-2-[4-(6-chloro-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163512(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50:  23.3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163538(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163548(CHEMBL537187 | N-(4-Acetyl-phenyl)-2-[4-(6-methyl-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163529(CHEMBL535824 | N-(9-Hydroxy-9H-fluoren-3-yl)-2-[4-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163511(CHEMBL536276 | N-(4-Benzoyl-phenyl)-2-[4-(8-methyl...)
Affinity DataIC50:  39.6nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163521(2-[4-(8-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163514(CHEMBL540365 | N-(9-Ethyl-9H-carbazol-3-yl)-2-[4-(...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163531(CHEMBL557817 | N-(9-Ethyl-9H-carbazol-3-yl)-2-[4-(...)
Affinity DataIC50:  54.6nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163540(CHEMBL365777 | N-Dibenzofuran-2-yl-2-[4-(8-methoxy...)
Affinity DataIC50:  55.7nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163550(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  60.7nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163530(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  69nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163533(2-[4-(6-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  86.7nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163524(2-[4-(5-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163519(2-[4-(6-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163522(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  112nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163549(CHEMBL556999 | N-(4-Cyano-phenyl)-2-[4-(2-oxo-4H-b...)
Affinity DataIC50:  132nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163520(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50:  138nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163547(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  148nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163532(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  199nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163528(CHEMBL558393 | N-(4-Chloro-phenyl)-2-[4-(2-oxo-4H-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163542(CHEMBL538569 | N-(9-Ethyl-9H-carbazol-3-yl)-2-[4-(...)
Affinity DataIC50:  765nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163544(2-{2-[4-(6-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163534(CHEMBL536729 | N-(2-Benzoyl-phenyl)-2-[4-(6-chloro...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163537(2-{2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50163523(CHEMBL534710 | N-(2-Benzoyl-phenyl)-2-[4-(2-oxo-4H...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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