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Compile Data Set for Download or QSAR

Found 2 hits of affinity data for UniProtKB/TrEMBL: Q920E5   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Farnesyl pyrophosphate synthase


(Mus musculus)
BDBM50247920
PNG
(ALENDRONATE SODIUM | Alendronate Sodium | Binosto ...)
Show SMILES [Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
Show InChI InChI=1S/C4H13NO7P2.Na/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);/q;+1/p-1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Korea University

Curated by ChEMBL


Assay Description
Inhibition of farnesyl diphosphate synthase in Balb/C mouse osteoclast assessed as reduction in [3H]MVL incorporation into nonsaponifiable lipids pre...


J Med Chem 62: 6063-6082 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00270
More data for this
Ligand-Target Pair
Farnesyl pyrophosphate synthase


(Mus musculus)
BDBM50247920
PNG
(ALENDRONATE SODIUM | Alendronate Sodium | Binosto ...)
Show SMILES [Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
Show InChI InChI=1S/C4H13NO7P2.Na/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);/q;+1/p-1
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Korea University

Curated by ChEMBL


Assay Description
Inhibition of farnesyl diphosphate synthase in Balb/C mouse osteoclast assessed as reduction in [3H]MVL incorporation into prenylated proteins preinc...


J Med Chem 62: 6063-6082 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00270
More data for this
Ligand-Target Pair