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Compile Data Set for Download or QSAR

Found 4 hits of affinity data for UniProtKB/TrEMBL: P28075   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteasome subunit beta type-5


(Rattus norvegicus)
BDBM50535250
PNG
(CHEMBL471604)
Show SMILES Oc1ccc(\C=C/C(C=C)c2ccc(O)cc2)cc1
Show InChI InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2/b6-3-
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Institute of Agricultural and Food Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...


Eur J Med Chem 167: 291-311 (2019)


Article DOI: 10.1016/j.ejmech.2019.01.044
More data for this
Ligand-Target Pair
Proteasome subunit beta type-5


(Rattus norvegicus)
BDBM50380997
PNG
(BROUSSONIN B)
Show SMILES COc1cc(O)ccc1CCCc1ccc(O)cc1
Show InChI InChI=1S/C16H18O3/c1-19-16-11-15(18)10-7-13(16)4-2-3-12-5-8-14(17)9-6-12/h5-11,17-18H,2-4H2,1H3
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Similars

Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Institute of Agricultural and Food Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...


Eur J Med Chem 167: 291-311 (2019)


Article DOI: 10.1016/j.ejmech.2019.01.044
More data for this
Ligand-Target Pair
Proteasome subunit beta type-5


(Rattus norvegicus)
BDBM50535252
PNG
(CHEMBL4457323)
Show SMILES Oc1ccc(CC2COc3cc(O)ccc3C2)cc1
Show InChI InChI=1S/C16H16O3/c17-14-4-1-11(2-5-14)7-12-8-13-3-6-15(18)9-16(13)19-10-12/h1-6,9,12,17-18H,7-8,10H2
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Institute of Agricultural and Food Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...


Eur J Med Chem 167: 291-311 (2019)


Article DOI: 10.1016/j.ejmech.2019.01.044
More data for this
Ligand-Target Pair
Proteasome subunit beta type-5


(Rattus norvegicus)
BDBM50535251
PNG
(CHEMBL1078369)
Show SMILES COc1cc(O)c(C(=O)c2ccc(O)cc2)c(O)c1
Show InChI InChI=1S/C14H12O5/c1-19-10-6-11(16)13(12(17)7-10)14(18)8-2-4-9(15)5-3-8/h2-7,15-17H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>250n/an/an/an/an/an/a



Institute of Agricultural and Food Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...


Eur J Med Chem 167: 291-311 (2019)


Article DOI: 10.1016/j.ejmech.2019.01.044
More data for this
Ligand-Target Pair