Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin F2-alpha receptor (Rattus norvegicus) | BDBM520995![]() ((+)-5-[({6-Bromo-3-methyl-2-[(2H8)pyrrolidin-1-yl]...) | KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Antagonist activity at rat FPR stably expressed in CHO cells assessed as inhibition of PGF2alpha-induced calcium flux preincubated for 10 mins follow... | J Med Chem 63: 11639-11662 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Rattus norvegicus) | BDBM520995![]() ((+)-5-[({6-Bromo-3-methyl-2-[(2H8)pyrrolidin-1-yl]...) | KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Antagonist activity at FPR in Wistar rat assessed as inhibition of PGF2alpha-induced uterus contraction | J Med Chem 63: 11639-11662 (2020) | |||||||||||
More data for this Ligand-Target Pair |