BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 6 hits of affinity data for UniProtKB/TrEMBL: O14791   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apolipoprotein L1


(Homo sapiens)
BDBM50547875
PNG
(CHEMBL4754532)
Show SMILES O[C@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(F)cc(F)cc12)-c1ccc(F)cc1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<250n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay


ACS Med Chem Lett 11: 2352-2353 (2020)

More data for this
Ligand-Target Pair
Apolipoprotein L1


(Homo sapiens)
BDBM50547876
PNG
(CHEMBL4791770)
Show SMILES Fc1cc(F)c2[nH]c(c(CCC(=O)N[C@H]3CCNC3=O)c2c1)-c1ccc(cc1)C#N
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<250n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay


ACS Med Chem Lett 11: 2352-2353 (2020)

More data for this
Ligand-Target Pair
Apolipoprotein L1


(Homo sapiens)
BDBM50547880
PNG
(CHEMBL4789274)
Show SMILES COc1ccc(cc1)-c1[nH]c2ccccc2c1CCC(=O)N[C@H]1[C@H](O)CNC1=O
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<250n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay


ACS Med Chem Lett 11: 2352-2353 (2020)

More data for this
Ligand-Target Pair
Apolipoprotein L1


(Homo sapiens)
BDBM50547878
PNG
(CHEMBL4752052)
Show SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(F)cccc12)-c1ccccc1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<250n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay


ACS Med Chem Lett 11: 2352-2353 (2020)

More data for this
Ligand-Target Pair
Apolipoprotein L1


(Homo sapiens)
BDBM50547879
PNG
(CHEMBL4780017)
Show SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2cc(F)c(F)cc12)-c1ccccc1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<250n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay


ACS Med Chem Lett 11: 2352-2353 (2020)

More data for this
Ligand-Target Pair
Apolipoprotein L1


(Homo sapiens)
BDBM50547877
PNG
(CHEMBL4795347)
Show SMILES O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c([nH]c2c(cc(F)cc12)C#N)-c1ccc(F)cc1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<250n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of APOL1 (unknown origin) in HEK293 cells assessed as thallium influx incubated for 30 mins by FLIPR based thallium influx assay


ACS Med Chem Lett 11: 2352-2353 (2020)

More data for this
Ligand-Target Pair