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Compile Data Set for Download or QSAR

Found 3 hits of affinity data for UniProtKB/TrEMBL: P0C7A3   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin O-acyltransferase


(Mus musculus)
BDBM50548065
PNG
(CHEMBL4785875)
Show SMILES Cc1nc(ccc1COc1cc(Cl)c2cc(CC(O)=O)sc2c1Cl)C(F)(F)F
Show InChI InChI=1S/C18H12Cl2F3NO3S/c1-8-9(2-3-14(24-8)18(21,22)23)7-27-13-6-12(19)11-4-10(5-15(25)26)28-17(11)16(13)20/h2-4,6H,5,7H2,1H3,(H,25,26)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a 3.10n/an/an/an/an/an/a



National Institute on Alcohol Abuse and Alcoholism

Curated by ChEMBL


Assay Description
Inhibition of mouse GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA -CoA as su...


RSC Med Chem 11: 1136-1144 (2020)

More data for this
Ligand-Target Pair
Ghrelin O-acyltransferase


(Mus musculus)
BDBM50548066
PNG
(CHEMBL4791105)
Show SMILES OC(=O)c1ccc2oc(SCc3ccc(Cl)cc3Cl)nc2c1
Show InChI InChI=1S/C15H9Cl2NO3S/c16-10-3-1-9(11(17)6-10)7-22-15-18-12-5-8(14(19)20)2-4-13(12)21-15/h1-6H,7H2,(H,19,20)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a 3.30n/an/an/an/an/an/a



National Institute on Alcohol Abuse and Alcoholism

Curated by ChEMBL


Assay Description
Inhibition of mouse GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA -CoA as su...


RSC Med Chem 11: 1136-1144 (2020)

More data for this
Ligand-Target Pair
Ghrelin O-acyltransferase


(Mus musculus)
BDBM50548069
PNG
(CHEMBL4741670)
Show SMILES CCCC[C@H]1C[C@@H](C1)C(=O)NC[C@H]1CCCN1C(=O)[C@@H](NC(=S)CNC)C(C)(C)C
Show InChI InChI=1S/C23H42N4O2S/c1-6-7-9-16-12-17(13-16)21(28)25-14-18-10-8-11-27(18)22(29)20(23(2,3)4)26-19(30)15-24-5/h16-18,20,24H,6-15H2,1-5H3,(H,25,28)(H,26,30)/t16-,17-,18-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a 30n/an/an/an/an/an/a



National Institute on Alcohol Abuse and Alcoholism

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His10-tagged mouse GOAT expressed in baculovirus infected sf9 insect cell membrane using proghrelin-His8 and [3H]octanoyl Co...


RSC Med Chem 11: 1136-1144 (2020)

More data for this
Ligand-Target Pair