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Compile Data Set for Download or QSAR

Found 5 hits of affinity data for UniProtKB/TrEMBL: Q96I25   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Splicing factor 45


(Homo sapiens)
BDBM50548170
PNG
(CHEMBL4799705)
Show SMILES N[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/a 960n/an/an/an/an/a



Helmholtz Zentrum M�nchen

Curated by ChEMBL


Assay Description
Binding affinity to His-Z-tagged SPF45 (unknown origin) UHM domain expressed in Escherichia coli BL21 (DE3) cells by ITC analysis


J Med Chem 59: 10190-10197 (2016)

More data for this
Ligand-Target Pair
Splicing factor 45


(Homo sapiens)
BDBM50548172
PNG
(CHEMBL4788784)
Show SMILES N[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/a 800n/an/an/an/an/a



Helmholtz Zentrum M�nchen

Curated by ChEMBL


Assay Description
Binding affinity to His-Z-tagged SPF45 (unknown origin) UHM domain expressed in Escherichia coli BL21 (DE3) cells by ITC analysis


J Med Chem 59: 10190-10197 (2016)

More data for this
Ligand-Target Pair
Splicing factor 45


(Homo sapiens)
BDBM50548176
PNG
(CHEMBL4747647)
Show SMILES NCCCC[C@H](NC(=O)[C@H]1CCC(=O)NCCCC[C@@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(O)=O)C(=O)N1)C(O)=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/a 180n/an/an/an/an/a



Helmholtz Zentrum M�nchen

Curated by ChEMBL


Assay Description
Binding affinity to His-Z-tagged SPF45 (unknown origin) UHM domain expressed in Escherichia coli BL21 (DE3) cells by ITC analysis


J Med Chem 59: 10190-10197 (2016)

More data for this
Ligand-Target Pair
Splicing factor 45


(Homo sapiens)
BDBM50548175
PNG
(CHEMBL4786448)
Show SMILES N[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC1=O)C(=O)NC(CCCCN=C(N)N)C(O)=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/a 750n/an/an/an/an/a



Helmholtz Zentrum M�nchen

Curated by ChEMBL


Assay Description
Binding affinity to His-Z-tagged SPF45 (unknown origin) UHM domain expressed in Escherichia coli BL21 (DE3) cells by ITC analysis


J Med Chem 59: 10190-10197 (2016)

More data for this
Ligand-Target Pair
Splicing factor 45


(Homo sapiens)
BDBM50548173
PNG
(CHEMBL4797754)
Show SMILES N[C@@H]1CCCCNC(=O)CC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/an/a 510n/an/an/an/an/a



Helmholtz Zentrum M�nchen

Curated by ChEMBL


Assay Description
Binding affinity to His-Z-tagged SPF45 (unknown origin) UHM domain expressed in Escherichia coli BL21 (DE3) cells by ITC analysis


J Med Chem 59: 10190-10197 (2016)

More data for this
Ligand-Target Pair