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Compile Data Set for Download or QSAR

Found 1 hit of affinity data for UniProtKB/TrEMBL: Q8R4K2   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-1 receptor-associated kinase 4


(Mus musculus)
BDBM207906
PNG
(US9546153, ex. 42)
Show SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC1CC1
Show InChI InChI=1S/C21H24FN5O2S/c1-21(2,29)18(22)10-24-20(28)14-9-23-19(8-16(14)26-12-3-4-12)27-13-5-6-15-17(7-13)30-11-25-15/h5-9,11-12,18,29H,3-4,10H2,1-2H3,(H,24,28)(H2,23,26,27)/t18-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Biocon Bristol Myers Squibb Research Center

Curated by ChEMBL


Assay Description
Inhibition of IRAK4 in mouse whole blood


ACS Med Chem Lett 11: 1402-1409 (2020)


Article DOI: 10.1021/acsmedchemlett.0c00082
More data for this
Ligand-Target Pair