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Compile Data Set for Download or QSAR

Found 2 hits of affinity data for UniProtKB/TrEMBL: Q13148   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TAR DNA-binding protein 43


(Homo sapiens)
BDBM50544712
PNG
(CHEMBL4635203)
Show SMILES COc1cc(NC(=O)CCC2CCCN(Cc3ccc(F)c(OC)c3)C2)cc(OC)c1
Show InChI InChI=1S/C24H31FN2O4/c1-29-20-12-19(13-21(14-20)30-2)26-24(28)9-7-17-5-4-10-27(15-17)16-18-6-8-22(25)23(11-18)31-3/h6,8,11-14,17H,4-5,7,9-10,15-16H2,1-3H3,(H,26,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a 100n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of TDP-43 (unknown origin) binding to RNA


Bioorg Med Chem Lett 30: (2020)

More data for this
Ligand-Target Pair
TAR DNA-binding protein 43


(Homo sapiens)
BDBM50544711
PNG
(CHEMBL4647070)
Show SMILES CCc1cccc(C)c1NS(=O)(=O)c1cnccc1C(=O)N1CCCC1
Show InChI InChI=1S/C19H23N3O3S/c1-3-15-8-6-7-14(2)18(15)21-26(24,25)17-13-20-10-9-16(17)19(23)22-11-4-5-12-22/h6-10,13,21H,3-5,11-12H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a<100n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of TDP-43 (unknown origin) binding to RNA


Bioorg Med Chem Lett 30: (2020)

More data for this
Ligand-Target Pair