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Compile Data Set for Download or QSAR

Found 5 hits of affinity data for UniProtKB/TrEMBL: Q9GZV9   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor 23


(Homo sapiens)
BDBM50549239
PNG
(CHEMBL4755048)
Show SMILES Cc1ccc(\C=C\c2ccccc2\C=N\O)cc1
Show InChI InChI=1S/C16H15NO/c1-13-6-8-14(9-7-13)10-11-15-4-2-3-5-16(15)12-17-18/h2-12,18H,1H3/b11-10+,17-12+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 140n/an/an/an/an/an/a



Tennessee Technological University

Curated by ChEMBL


Assay Description
Inhibition of FGF23 (unknown origin)-mediated activation of FGFR/alpha-Klotho transfected in HEK293T cells cotransfected with ERK luciferase reporter...


Bioorg Med Chem 29: (2021)

More data for this
Ligand-Target Pair
Fibroblast growth factor 23


(Homo sapiens)
BDBM50549233
PNG
(CHEMBL4790497)
Show SMILES Cc1ccc(\C=C\C2=C(CCC2)/C=N/O)cc1
Show InChI InChI=1S/C15H17NO/c1-12-5-7-13(8-6-12)9-10-14-3-2-4-15(14)11-16-17/h5-11,17H,2-4H2,1H3/b10-9+,16-11+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 200n/an/an/an/an/an/a



Tennessee Technological University

Curated by ChEMBL


Assay Description
Inhibition of FGF23 (unknown origin)-mediated activation of FGFR/alpha-Klotho transfected in HEK293T cells cotransfected with ERK luciferase reporter...


Bioorg Med Chem 29: (2021)

More data for this
Ligand-Target Pair
Fibroblast growth factor 23


(Homo sapiens)
BDBM50549234
PNG
(CHEMBL4798326)
Show SMILES O\N=C\C1=C(CCC1)/C=C/c1ccc(F)cc1
Show InChI InChI=1S/C14H14FNO/c15-14-8-5-11(6-9-14)4-7-12-2-1-3-13(12)10-16-17/h4-10,17H,1-3H2/b7-4+,16-10+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 370n/an/an/an/an/an/a



Tennessee Technological University

Curated by ChEMBL


Assay Description
Inhibition of FGF23 (unknown origin)-mediated activation of FGFR/alpha-Klotho transfected in HEK293T cells cotransfected with ERK luciferase reporter...


Bioorg Med Chem 29: (2021)

More data for this
Ligand-Target Pair
Fibroblast growth factor 23


(Homo sapiens)
BDBM50549240
PNG
(CHEMBL4749792)
Show SMILES Cc1ccc(\C=C\c2ncccc2\C=N\O)cc1
Show InChI InChI=1S/C15H14N2O/c1-12-4-6-13(7-5-12)8-9-15-14(11-17-18)3-2-10-16-15/h2-11,18H,1H3/b9-8+,17-11+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 390n/an/an/an/an/an/a



Tennessee Technological University

Curated by ChEMBL


Assay Description
Inhibition of FGF23 (unknown origin)-mediated activation of FGFR/alpha-Klotho transfected in HEK293T cells cotransfected with ERK luciferase reporter...


Bioorg Med Chem 29: (2021)

More data for this
Ligand-Target Pair
Fibroblast growth factor 23


(Homo sapiens)
BDBM50549238
PNG
(CHEMBL4781167)
Show SMILES Cc1ccc(\C=C\C2=C(CCCC2)/C=N/O)cc1
Show InChI InChI=1S/C16H19NO/c1-13-6-8-14(9-7-13)10-11-15-4-2-3-5-16(15)12-17-18/h6-12,18H,2-5H2,1H3/b11-10+,17-12+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 520n/an/an/an/an/an/a



Tennessee Technological University

Curated by ChEMBL


Assay Description
Inhibition of FGF23 (unknown origin)-mediated activation of FGFR/alpha-Klotho transfected in HEK293T cells cotransfected with ERK luciferase reporter...


Bioorg Med Chem 29: (2021)

More data for this
Ligand-Target Pair