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Compile Data Set for Download or QSAR

Found 3 hits of affinity data for UniProtKB/TrEMBL: O08725   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Growth hormone secretagogue receptor type 1


(Rattus norvegicus)
BDBM50552132
PNG
(SPIROPIPERIDINE | Spiropiperidine)
Show SMILES O=C(NC(Cc1c[nH]c2ccccc12)C(=O)N1CCC2(CCc3ccccc23)CC1)NC1CN2CCC1CC2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 50n/an/an/an/a



St. John's University

Curated by ChEMBL


Assay Description
Agonist activity at GHSR in Wistar rat pituitary gland cells assessed as induction of GH release by RIA


J Med Chem 63: 13291-13315 (2020)

More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Rattus norvegicus)
BDBM50083974
PNG
(2-Amino-N-[(R)-2-((R)-3a-benzyl-2-methyl-3-oxo-2,3...)
Show SMILES CN1N=C2CCN(C[C@@]2(Cc2ccccc2)C1=O)C(=O)[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N
Show InChI InChI=1S/C28H35N5O4/c1-27(2,29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33,26(36)32(3)31-23)16-20-10-6-4-7-11-20/h4-13,22H,14-19,29H2,1-3H3,(H,30,35)/t22-,28-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/an/an/a 3n/an/an/an/a



St. John's University

Curated by ChEMBL


Assay Description
Agonist activity at GHSR in Wistar rat pituitary gland cells assessed as induction of GH release by RIA


J Med Chem 63: 13291-13315 (2020)

More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Rattus norvegicus)
BDBM50552133
PNG
(CHEMBL4765101)
Show SMILES CC(C)(N)NC(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CC(c3ccccc23)S(C)(=O)=O)CC1
Show InChI InChI=1S/C28H38N4O5S/c1-27(2,29)31-26(34)30-23(19-37-18-20-9-5-4-6-10-20)25(33)32-15-13-28(14-16-32)17-24(38(3,35)36)21-11-7-8-12-22(21)28/h4-12,23-24H,13-19,29H2,1-3H3,(H2,30,31,34)/t23-,24?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 1.30n/an/an/an/a



St. John's University

Curated by ChEMBL


Assay Description
Agonist activity at GHSR in Wistar rat pituitary gland cells assessed as induction of GH release by RIA


J Med Chem 63: 13291-13315 (2020)

More data for this
Ligand-Target Pair