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Compile Data Set for Download or QSAR

Found 34 hits of affinity data for UniProtKB/TrEMBL: Q6IQ20   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557066
PNG
(CHEMBL4794048)
Show SMILES O[C@H]1CCN(C1)c1cc(nc(n1)N1CCC[C@H](C1)c1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C24H31N5O2/c30-20-10-12-28(16-20)22-13-21(23(31)25-14-17-8-9-17)26-24(27-22)29-11-4-7-19(15-29)18-5-2-1-3-6-18/h1-3,5-6,13,17,19-20,30H,4,7-12,14-16H2,(H,25,31)/t19-,20+/m1/s1
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n/an/a 72n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557063
PNG
(CHEMBL4761882)
Show SMILES O[C@@H]1CCN(C1)c1cc(nc(n1)N1CCC[C@H](C1)c1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C24H31N5O2/c30-20-10-12-28(16-20)22-13-21(23(31)25-14-17-8-9-17)26-24(27-22)29-11-4-7-19(15-29)18-5-2-1-3-6-18/h1-3,5-6,13,17,19-20,30H,4,7-12,14-16H2,(H,25,31)/t19-,20-/m1/s1
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Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557059
PNG
(CHEMBL4782800)
Show SMILES CN(C)c1cc(nc(n1)N1CCC[C@H](C1)c1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C22H29N5O/c1-26(2)20-13-19(21(28)23-14-16-10-11-16)24-22(25-20)27-12-6-9-18(15-27)17-7-4-3-5-8-17/h3-5,7-8,13,16,18H,6,9-12,14-15H2,1-2H3,(H,23,28)/t18-/m1/s1
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n/an/a 112n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557054
PNG
(CHEMBL4752937)
Show SMILES CN(CCc1ccccc1)c1cc(nc(n1)N(C)CCc1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C27H33N5O/c1-31(17-15-21-9-5-3-6-10-21)25-19-24(26(33)28-20-23-13-14-23)29-27(30-25)32(2)18-16-22-11-7-4-8-12-22/h3-12,19,23H,13-18,20H2,1-2H3,(H,28,33)
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n/an/a 155n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557061
PNG
(CHEMBL4754918)
Show SMILES O=C(NCC1CC1)c1cc(nc(n1)N1CCC[C@H](C1)c1ccccc1)N1CCOCC1
Show InChI InChI=1S/C24H31N5O2/c30-23(25-16-18-8-9-18)21-15-22(28-11-13-31-14-12-28)27-24(26-21)29-10-4-7-20(17-29)19-5-2-1-3-6-19/h1-3,5-6,15,18,20H,4,7-14,16-17H2,(H,25,30)/t20-/m1/s1
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n/an/a 209n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557045
PNG
(CHEMBL4751223)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCCC1
Show InChI InChI=1S/C22H29N5O/c1-26(14-11-17-7-3-2-4-8-17)22-24-19(21(28)23-16-18-9-10-18)15-20(25-22)27-12-5-6-13-27/h2-4,7-8,15,18H,5-6,9-14,16H2,1H3,(H,23,28)
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n/an/a 224n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557047
PNG
(CHEMBL4783103)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCC(O)C1
Show InChI InChI=1S/C22H29N5O2/c1-26(11-9-16-5-3-2-4-6-16)22-24-19(21(29)23-14-17-7-8-17)13-20(25-22)27-12-10-18(28)15-27/h2-6,13,17-18,28H,7-12,14-15H2,1H3,(H,23,29)
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n/an/a 224n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557049
PNG
(CHEMBL4759968)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CC[C@H](O)C1
Show InChI InChI=1S/C22H29N5O2/c1-26(11-9-16-5-3-2-4-6-16)22-24-19(21(29)23-14-17-7-8-17)13-20(25-22)27-12-10-18(28)15-27/h2-6,13,17-18,28H,7-12,14-15H2,1H3,(H,23,29)/t18-/m0/s1
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n/an/a 234n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557064
PNG
(CHEMBL4760293)
Show SMILES O[C@H]1CCN(C1)c1cc(nc(n1)N1CCC[C@@H](C1)c1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C24H31N5O2/c30-20-10-12-28(16-20)22-13-21(23(31)25-14-17-8-9-17)26-24(27-22)29-11-4-7-19(15-29)18-5-2-1-3-6-18/h1-3,5-6,13,17,19-20,30H,4,7-12,14-16H2,(H,25,31)/t19-,20-/m0/s1
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Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557013
PNG
(CHEMBL4752023)
Show SMILES CC(C)N(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C24H33N5O2/c1-18(2)29(11-10-19-6-4-3-5-7-19)24-26-21(23(30)25-17-20-8-9-20)16-22(27-24)28-12-14-31-15-13-28/h3-7,16,18,20H,8-15,17H2,1-2H3,(H,25,30)
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n/an/a 282n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557039
PNG
(CHEMBL4747615)
Show SMILES CN(C)c1cc(nc(n1)N(C)CCc1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C20H27N5O/c1-24(2)18-13-17(19(26)21-14-16-9-10-16)22-20(23-18)25(3)12-11-15-7-5-4-6-8-15/h4-8,13,16H,9-12,14H2,1-3H3,(H,21,26)
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n/an/a 288n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557048
PNG
(CHEMBL4764910)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CC[C@@H](O)C1
Show InChI InChI=1S/C22H29N5O2/c1-26(11-9-16-5-3-2-4-6-16)22-24-19(21(29)23-14-17-7-8-17)13-20(25-22)27-12-10-18(28)15-27/h2-6,13,17-18,28H,7-12,14-15H2,1H3,(H,23,29)/t18-/m1/s1
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Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557065
PNG
(CHEMBL4750592)
Show SMILES O[C@@H]1CCN(C1)c1cc(nc(n1)N1CCC[C@@H](C1)c1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C24H31N5O2/c30-20-10-12-28(16-20)22-13-21(23(31)25-14-17-8-9-17)26-24(27-22)29-11-4-7-19(15-29)18-5-2-1-3-6-18/h1-3,5-6,13,17,19-20,30H,4,7-12,14-16H2,(H,25,31)/t19-,20+/m0/s1
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n/an/a 324n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557020
PNG
(CHEMBL4760794)
Show SMILES O=C(NCC1CC1)c1cc(nc(n1)N1CCCC(C1)c1ccccc1)N1CCOCC1
Show InChI InChI=1S/C24H31N5O2/c30-23(25-16-18-8-9-18)21-15-22(28-11-13-31-14-12-28)27-24(26-21)29-10-4-7-20(17-29)19-5-2-1-3-6-19/h1-3,5-6,15,18,20H,4,7-14,16-17H2,(H,25,30)
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n/an/a 380n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557021
PNG
(CHEMBL4752088)
Show SMILES O=C(NCC1CC1)c1cc(nc(n1)N1CCCC1Cc1ccccc1)N1CCOCC1
Show InChI InChI=1S/C24H31N5O2/c30-23(25-17-19-8-9-19)21-16-22(28-11-13-31-14-12-28)27-24(26-21)29-10-4-7-20(29)15-18-5-2-1-3-6-18/h1-3,5-6,16,19-20H,4,7-15,17H2,(H,25,30)
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n/an/a 380n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557030
PNG
(CHEMBL4746912)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCCC(F)(F)C1
Show InChI InChI=1S/C23H29F2N5O/c1-29(13-10-17-6-3-2-4-7-17)22-27-19(21(31)26-15-18-8-9-18)14-20(28-22)30-12-5-11-23(24,25)16-30/h2-4,6-7,14,18H,5,8-13,15-16H2,1H3,(H,26,31)
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n/an/a 389n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557060
PNG
(CHEMBL4750134)
Show SMILES CN(C)c1cc(nc(n1)N1CCC[C@@H](C1)c1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C22H29N5O/c1-26(2)20-13-19(21(28)23-14-16-10-11-16)24-22(25-20)27-12-6-9-18(15-27)17-7-4-3-5-8-17/h3-5,7-8,13,16,18H,6,9-12,14-15H2,1-2H3,(H,23,28)/t18-/m0/s1
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Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557043
PNG
(CHEMBL4795010)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCC1
Show InChI InChI=1S/C21H27N5O/c1-25(13-10-16-6-3-2-4-7-16)21-23-18(20(27)22-15-17-8-9-17)14-19(24-21)26-11-5-12-26/h2-4,6-7,14,17H,5,8-13,15H2,1H3,(H,22,27)
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Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557007
PNG
(CHEMBL4764783)
Show SMILES CN(CCc1ccccc1-c1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C28H33N5O2/c1-32(14-13-23-9-5-6-10-24(23)22-7-3-2-4-8-22)28-30-25(27(34)29-20-21-11-12-21)19-26(31-28)33-15-17-35-18-16-33/h2-10,19,21H,11-18,20H2,1H3,(H,29,34)
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n/an/a 490n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557042
PNG
(CHEMBL4787774)
Show SMILES CCN(CC)c1cc(nc(n1)N(C)CCc1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C22H31N5O/c1-4-27(5-2)20-15-19(21(28)23-16-18-11-12-18)24-22(25-20)26(3)14-13-17-9-7-6-8-10-17/h6-10,15,18H,4-5,11-14,16H2,1-3H3,(H,23,28)
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Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557017
PNG
(CHEMBL4743071)
Show SMILES O=C(NCC1CC1)c1cc(nc(n1)N(CCc1ccccc1)CCc1ccccc1)N1CCOCC1
Show InChI InChI=1S/C29H35N5O2/c35-28(30-22-25-11-12-25)26-21-27(33-17-19-36-20-18-33)32-29(31-26)34(15-13-23-7-3-1-4-8-23)16-14-24-9-5-2-6-10-24/h1-10,21,25H,11-20,22H2,(H,30,35)
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n/an/a 525n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557006
PNG
(CHEMBL4750396)
Show SMILES CN(CCc1ccccc1Oc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C28H33N5O3/c1-32(14-13-22-7-5-6-10-25(22)36-23-8-3-2-4-9-23)28-30-24(27(34)29-20-21-11-12-21)19-26(31-28)33-15-17-35-18-16-33/h2-10,19,21H,11-18,20H2,1H3,(H,29,34)
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n/an/a 603n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557012
PNG
(CHEMBL4756143)
Show SMILES CCN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C23H31N5O2/c1-2-27(11-10-18-6-4-3-5-7-18)23-25-20(22(29)24-17-19-8-9-19)16-21(26-23)28-12-14-30-15-13-28/h3-7,16,19H,2,8-15,17H2,1H3,(H,24,29)
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n/an/a 646n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557029
PNG
(CHEMBL4741598)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCCCC1
Show InChI InChI=1S/C23H31N5O/c1-27(15-12-18-8-4-2-5-9-18)23-25-20(22(29)24-17-19-10-11-19)16-21(26-23)28-13-6-3-7-14-28/h2,4-5,8-9,16,19H,3,6-7,10-15,17H2,1H3,(H,24,29)
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n/an/a 646n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557050
PNG
(CHEMBL4792394)
Show SMILES COC1CCN(C1)c1cc(nc(n1)N(C)CCc1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C23H31N5O2/c1-27(12-10-17-6-4-3-5-7-17)23-25-20(22(29)24-15-18-8-9-18)14-21(26-23)28-13-11-19(16-28)30-2/h3-7,14,18-19H,8-13,15-16H2,1-2H3,(H,24,29)
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n/an/a 708n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557022
PNG
(CHEMBL4787757)
Show SMILES O=C(NCC1CC1)c1cc(nc(n1)N1CCCCC1Cc1ccccc1)N1CCOCC1
Show InChI InChI=1S/C25H33N5O2/c31-24(26-18-20-9-10-20)22-17-23(29-12-14-32-15-13-29)28-25(27-22)30-11-5-4-8-21(30)16-19-6-2-1-3-7-19/h1-3,6-7,17,20-21H,4-5,8-16,18H2,(H,26,31)
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n/an/a 741n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557016
PNG
(CHEMBL4764562)
Show SMILES O=C(NCC1CC1)c1cc(nc(n1)N(CCc1ccccc1)Cc1ccccc1)N1CCOCC1
Show InChI InChI=1S/C28H33N5O2/c34-27(29-20-23-11-12-23)25-19-26(32-15-17-35-18-16-32)31-28(30-25)33(21-24-9-5-2-6-10-24)14-13-22-7-3-1-4-8-22/h1-10,19,23H,11-18,20-21H2,(H,29,34)
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n/an/a 741n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557002
PNG
(CHEMBL4795013)
Show SMILES COc1ccccc1CCN(C)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C23H31N5O3/c1-27(10-9-18-5-3-4-6-20(18)30-2)23-25-19(22(29)24-16-17-7-8-17)15-21(26-23)28-11-13-31-14-12-28/h3-6,15,17H,7-14,16H2,1-2H3,(H,24,29)
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n/an/a 776n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50556960
PNG
(CHEMBL4790197)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C22H29N5O2/c1-26(10-9-17-5-3-2-4-6-17)22-24-19(21(28)23-16-18-7-8-18)15-20(25-22)27-11-13-29-14-12-27/h2-6,15,18H,7-14,16H2,1H3,(H,23,28)
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n/an/a 813n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50556979
PNG
(CHEMBL4747267)
Show SMILES COC(=O)CNC(=O)c1cc(nc(n1)N(C)CCc1ccccc1)N1CCOCC1
Show InChI InChI=1S/C21H27N5O4/c1-25(9-8-16-6-4-3-5-7-16)21-23-17(20(28)22-15-19(27)29-2)14-18(24-21)26-10-12-30-13-11-26/h3-7,14H,8-13,15H2,1-2H3,(H,22,28)
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n/an/a 832n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557040
PNG
(CHEMBL4762577)
Show SMILES CNc1cc(nc(n1)N(C)CCc1ccccc1)C(=O)NCC1CC1
Show InChI InChI=1S/C19H25N5O/c1-20-17-12-16(18(25)21-13-15-8-9-15)22-19(23-17)24(2)11-10-14-6-4-3-5-7-14/h3-7,12,15H,8-11,13H2,1-2H3,(H,21,25)(H,20,22,23)
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n/an/a 851n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50557000
PNG
(CHEMBL4789858)
Show SMILES CN(CCc1ccccc1C)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C23H31N5O2/c1-17-5-3-4-6-19(17)9-10-27(2)23-25-20(22(29)24-16-18-7-8-18)15-21(26-23)28-11-13-30-14-12-28/h3-6,15,18H,7-14,16H2,1-2H3,(H,24,29)
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n/an/a 891n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50556975
PNG
(CHEMBL4795197)
Show SMILES CN(CCc1ccccc1)c1nc(cc(n1)C(=O)NCC#C)N1CCOCC1
Show InChI InChI=1S/C21H25N5O2/c1-3-10-22-20(27)18-16-19(26-12-14-28-15-13-26)24-21(23-18)25(2)11-9-17-7-5-4-6-8-17/h1,4-8,16H,9-15H2,2H3,(H,22,27)
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n/an/a 912n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D


(Homo sapiens)
BDBM50556998
PNG
(CHEMBL4745098)
Show SMILES CN(CCc1ccccc1Cl)c1nc(cc(n1)C(=O)NCC1CC1)N1CCOCC1
Show InChI InChI=1S/C22H28ClN5O2/c1-27(9-8-17-4-2-3-5-18(17)23)22-25-19(21(29)24-15-16-6-7-16)14-20(26-22)28-10-12-30-13-11-28/h2-5,14,16H,6-13,15H2,1H3,(H,24,29)
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n/an/a 977n/an/an/an/an/an/a



Leiden University and Oncode Institute

Curated by ChEMBL


Assay Description
Inhibition of full length human NAPE-PLD expressed in HEK293T cell lysate using PED6 as substrate preincubated for 30 mins followed by substrate addi...


J Med Chem 64: 481-515 (2021)

More data for this
Ligand-Target Pair