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Compile Data Set for Download or QSAR

Found 1 hit of affinity data for UniProtKB/TrEMBL: Q6P6C2   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA demethylase ALKBH5


(Homo sapiens)		BDBM50557836
PNG
(CHEMBL4752151)
Show SMILES OC(SCC(O)=O)C(=O)c1ccccc1
Show InChI InChI=1S/C10H10O4S/c11-8(12)6-15-10(14)9(13)7-4-2-1-3-5-7/h1-5,10,14H,6H2,(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a 840n/an/an/an/an/an/a



Smith, Gambrell & Russell LLP

Curated by ChEMBL


Assay Description
Inhibition of ALKBH5 demethylase activity (unknown origin) assessed as increase in methylated 6A-RNA level incubated for 2 hrs by colorimetric analys...

ACS Med Chem Lett 12: 856-857 (2021)

More data for this
Ligand-Target Pair