BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits of affinity data for UniProtKB/TrEMBL: D4A7K7   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 183


(Rattus norvegicus)
BDBM50558426
PNG
(CHEMBL4788348)
Show SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Show InChI InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

KEGG
PC cid
PC sid
PDB
UniChem
PDB
PubMed
n/an/an/an/a 1.30n/an/an/an/a



Janssen Research & Development, LLC

Curated by ChEMBL


Assay Description
Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 min...


Bioorg Med Chem Lett 26: 4888-4891 (2016)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
G-protein coupled receptor 183


(Rattus norvegicus)
BDBM50558428
PNG
(CHEMBL4779254)
Show SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@@]1(C)CC[C@H](O)CC1=C[C@]3(O)C(F)(F)F
Show InChI InChI=1S/C28H45F3O3/c1-17(7-6-12-24(2,3)33)20-8-9-21-23-22(11-14-26(20,21)5)25(4)13-10-19(32)15-18(25)16-27(23,34)28(29,30)31/h16-17,19-23,32-34H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23+,25+,26-,27-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 1.10n/an/an/an/a



Janssen Research & Development, LLC

Curated by ChEMBL


Assay Description
Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 min...


Bioorg Med Chem Lett 26: 4888-4891 (2016)

More data for this
Ligand-Target Pair
G-protein coupled receptor 183


(Rattus norvegicus)
BDBM50558427
PNG
(CHEMBL4757291)
Show SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@@]1(C)CC[C@H](O)CC1=C[C@@]3(O)C(F)(F)F
Show InChI InChI=1S/C28H45F3O3/c1-17(7-6-12-24(2,3)33)20-8-9-21-23-22(11-14-26(20,21)5)25(4)13-10-19(32)15-18(25)16-27(23,34)28(29,30)31/h16-17,19-23,32-34H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23+,25+,26-,27+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 14n/an/an/an/a



Janssen Research & Development, LLC

Curated by ChEMBL


Assay Description
Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 min...


Bioorg Med Chem Lett 26: 4888-4891 (2016)

More data for this
Ligand-Target Pair