Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled receptor 183 (Rattus norvegicus) | BDBM50558426![]() (CHEMBL4788348) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase KEGG PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
Janssen Research & Development, LLC Curated by ChEMBL | Assay Description Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 min... | Bioorg Med Chem Lett 26: 4888-4891 (2016) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
G-protein coupled receptor 183 (Rattus norvegicus) | BDBM50558428![]() (CHEMBL4779254) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
Janssen Research & Development, LLC Curated by ChEMBL | Assay Description Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 min... | Bioorg Med Chem Lett 26: 4888-4891 (2016) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 183 (Rattus norvegicus) | BDBM50558427![]() (CHEMBL4757291) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Janssen Research & Development, LLC Curated by ChEMBL | Assay Description Agonist activity at Go2-q-coupled rat EBI2 expressed in COS7 cell membranes assessed as stimulation of [35S]GTPgammaS binding preincubated for 20 min... | Bioorg Med Chem Lett 26: 4888-4891 (2016) | |||||||||||
More data for this Ligand-Target Pair |