Compile Data Set for Download or QSAR
Found 3 of ic50 for UniProtKB: P62812
TargetGamma-aminobutyric acid receptor subunit alpha-1(Mus musculus)
Centre de Neurochimie du CNRS

Curated by ChEMBL
LigandPNGBDBM50001561(5-(6-Imino-3-thiophen-3-yl-6H-pyridazin-1-ylmethyl...)
Show SMILES N=c1ccc(nn1Cc1cc(=O)[nH]o1)-c1ccsc1
Show InChI InChI=1S/C12H10N4O2S/c13-11-2-1-10(8-3-4-19-7-8)14-16(11)6-9-5-12(17)15-18-9/h1-5,7,13H,6H2,(H,15,17)
Affinity DataIC50: 88nMAssay Description:Affinity for gamma-aminobutyric-acid A receptor measured by its ability to displace [3H]gabazine antagonist from rat brain preparations.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Mus musculus)
Centre de Neurochimie du CNRS

Curated by ChEMBL
LigandPNGBDBM50001562(5-(6-Imino-3-phenyl-6H-pyridazin-1-ylmethyl)-isoxa...)
Show SMILES N=c1ccc(nn1Cc1cc(=O)[nH]o1)-c1ccccc1
Show InChI InChI=1S/C14H12N4O2/c15-13-7-6-12(10-4-2-1-3-5-10)16-18(13)9-11-8-14(19)17-20-11/h1-8,15H,9H2,(H,17,19)
Affinity DataIC50: 240nMAssay Description:Affinity for gamma-aminobutyric-acid A receptor measured by its ability to displace [3H]gabazine antagonist from rat brain preparations.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Mus musculus)
Centre de Neurochimie du CNRS

Curated by ChEMBL
LigandPNGBDBM50001556(4-(6-Imino-5-methyl-3-phenyl-6H-pyridazin-1-yl)-bu...)
Show SMILES Cc1cc(nn(CCCC(O)=O)c1=N)-c1ccccc1
Show InChI InChI=1S/C15H17N3O2/c1-11-10-13(12-6-3-2-4-7-12)17-18(15(11)16)9-5-8-14(19)20/h2-4,6-7,10,16H,5,8-9H2,1H3,(H,19,20)
Affinity DataIC50: 800nMAssay Description:Affinity for gamma-aminobutyric-acid A receptor measured by its ability to displace [3H]gabazine antagonist from rat brain preparations.More data for this Ligand-Target Pair