BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 34 hits of ec50 for UniProtKB: P29276   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50389797
PNG
(CHEMBL261482)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1CC1
Show InChI InChI=1S/C13H16N6O4/c14-10-6-11(16-3-15-10)19(4-17-6)13-8(21)7(20)9(23-13)12(22)18-5-1-2-5/h3-5,7-9,13,20-21H,1-2H2,(H,18,22)(H2,14,15,16)/t7-,8+,9-,13+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 110n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM21220
PNG
((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/an/an/a 130n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452315
PNG
(CHEMBL2094086)
Show SMILES CC[C@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C20H23N5O5/c1-2-12(8-11-6-4-3-5-7-11)24-17-13-18(22-9-21-17)25(10-23-13)19-15(27)14(26)16(30-19)20(28)29/h3-7,9-10,12,14-16,19,26-27H,2,8H2,1H3,(H,28,29)(H,21,22,24)/t12-,14+,15-,16+,19-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 280n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452316
PNG
(CHEMBL2094084)
Show SMILES C[C@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C19H21N5O5/c1-10(7-11-5-3-2-4-6-11)23-16-12-17(21-8-20-16)24(9-22-12)18-14(26)13(25)15(29-18)19(27)28/h2-6,8-10,13-15,18,25-26H,7H2,1H3,(H,27,28)(H,20,21,23)/t10-,13+,14-,15+,18-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 340n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367386
PNG
(CHEMBL603571)
Show SMILES COc1cc(CCNc2ncnc3n(cnc23)C2O[C@@H]([C@@H](O)[C@H]2O)C(O)=O)cc(OC)c1OC
Show InChI InChI=1S/C21H25N5O8/c1-31-11-6-10(7-12(32-2)16(11)33-3)4-5-22-18-13-19(24-8-23-18)26(9-25-13)20-15(28)14(27)17(34-20)21(29)30/h6-9,14-15,17,20,27-28H,4-5H2,1-3H3,(H,29,30)(H,22,23,24)/t14-,15+,17-,20?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 420n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367388
PNG
(CHEMBL606501)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1CC1
Show InChI InChI=1S/C18H26N6O4/c1-3-9(4-2)22-15-11-16(20-7-19-15)24(8-21-11)18-13(26)12(25)14(28-18)17(27)23-10-5-6-10/h7-10,12-14,18,25-26H,3-6H2,1-2H3,(H,23,27)(H,19,20,22)/t12-,13+,14-,18?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 540n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50407975
PNG
(CHEMBL519809)
Show SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C11H14N6O4/c1-13-10(20)7-5(18)6(19)11(21-7)17-3-16-4-8(12)14-2-15-9(4)17/h2-3,5-7,11,18-19H,1H3,(H,13,20)(H2,12,14,15)/t5-,6+,7-,11+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 720n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452317
PNG
(CHEMBL2094085)
Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@H](CC)Cc3ccccc3)ncnc12
Show InChI InChI=1S/C22H28N6O4/c1-3-14(10-13-8-6-5-7-9-13)27-19-15-20(25-11-24-19)28(12-26-15)22-17(30)16(29)18(32-22)21(31)23-4-2/h5-9,11-12,14,16-18,22,29-30H,3-4,10H2,1-2H3,(H,23,31)(H,24,25,27)/t14-,16+,17-,18+,22-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 820n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367387
PNG
(CHEMBL606503)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C15H21N5O5/c1-3-7(4-2)19-12-8-13(17-5-16-12)20(6-18-8)14-10(22)9(21)11(25-14)15(23)24/h5-7,9-11,14,21-22H,3-4H2,1-2H3,(H,23,24)(H,16,17,19)/t9-,10+,11-,14?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 820n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452322
PNG
(CHEMBL2093998)
Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@H](C)Cc3ccccc3)ncnc12
Show InChI InChI=1S/C21H26N6O4/c1-3-22-20(30)17-15(28)16(29)21(31-17)27-11-25-14-18(23-10-24-19(14)27)26-12(2)9-13-7-5-4-6-8-13/h4-8,10-12,15-17,21,28-29H,3,9H2,1-2H3,(H,22,30)(H,23,24,26)/t12-,15+,16-,17+,21-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 980n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367375
PNG
(CHEMBL604834)
Show SMILES COc1ccc(Nc2ncnc3n(cnc23)C2O[C@@H]([C@@H](O)[C@H]2O)C(O)=O)cc1
Show InChI InChI=1S/C17H17N5O6/c1-27-9-4-2-8(3-5-9)21-14-10-15(19-6-18-14)22(7-20-10)16-12(24)11(23)13(28-16)17(25)26/h2-7,11-13,16,23-24H,1H3,(H,25,26)(H,18,19,21)/t11-,12+,13-,16?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.20E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367380
PNG
(CHEMBL605449)
Show SMILES CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC(CC)CC)ncnc12
Show InChI InChI=1S/C17H26N6O4/c1-4-9(5-2)22-14-10-15(20-7-19-14)23(8-21-10)17-12(25)11(24)13(27-17)16(26)18-6-3/h7-9,11-13,17,24-25H,4-6H2,1-3H3,(H,18,26)(H,19,20,22)/t11-,12+,13-,17?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.20E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367385
PNG
(CHEMBL605863)
Show SMILES O[C@H]1[C@@H](O)C(O[C@@H]1C(O)=O)n1cnc2c(NC3CCCCC3)ncnc12
Show InChI InChI=1S/C16H21N5O5/c22-10-11(23)15(26-12(10)16(24)25)21-7-19-9-13(17-6-18-14(9)21)20-8-4-2-1-3-5-8/h6-8,10-12,15,22-23H,1-5H2,(H,24,25)(H,17,18,20)/t10-,11+,12-,15?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367376
PNG
(CHEMBL605866)
Show SMILES NC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C10H12N6O4/c11-7-3-9(14-1-13-7)16(2-15-3)10-5(18)4(17)6(20-10)8(12)19/h1-2,4-6,10,17-18H,(H2,12,19)(H2,11,13,14)/t4-,5+,6-,10?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.56E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367364
PNG
(CHEMBL603990)
Show SMILES CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(Nc3ccc(OC)cc3)ncnc12
Show InChI InChI=1S/C19H22N6O5/c1-3-20-18(28)15-13(26)14(27)19(30-15)25-9-23-12-16(21-8-22-17(12)25)24-10-4-6-11(29-2)7-5-10/h4-9,13-15,19,26-27H,3H2,1-2H3,(H,20,28)(H,21,22,24)/t13-,14+,15-,19?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.80E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367383
PNG
(CHEMBL604207)
Show SMILES CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCCC3)ncnc12
Show InChI InChI=1S/C18H26N6O4/c1-2-19-17(27)14-12(25)13(26)18(28-14)24-9-22-11-15(20-8-21-16(11)24)23-10-6-4-3-5-7-10/h8-10,12-14,18,25-26H,2-7H2,1H3,(H,19,27)(H,20,21,23)/t12-,13+,14-,18?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.83E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452318
PNG
(CHEMBL2093995)
Show SMILES CC[C@@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C20H23N5O5/c1-2-12(8-11-6-4-3-5-7-11)24-17-13-18(22-9-21-17)25(10-23-13)19-15(27)14(26)16(30-19)20(28)29/h3-7,9-10,12,14-16,19,26-27H,2,8H2,1H3,(H,28,29)(H,21,22,24)/t12-,14-,15+,16-,19+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.20E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367368
PNG
(CHEMBL606290)
Show SMILES CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NCCc3cc(OC)c(OC)c(OC)c3)ncnc12
Show InChI InChI=1S/C23H30N6O7/c1-5-24-22(32)19-16(30)17(31)23(36-19)29-11-28-15-20(26-10-27-21(15)29)25-7-6-12-8-13(33-2)18(35-4)14(9-12)34-3/h8-11,16-17,19,23,30-31H,5-7H2,1-4H3,(H,24,32)(H,25,26,27)/t16-,17+,19-,23?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.20E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452320
PNG
(CHEMBL2093996)
Show SMILES C[C@@H](Cc1ccccc1)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C19H21N5O5/c1-10(7-11-5-3-2-4-6-11)23-16-12-17(21-8-20-16)24(9-22-12)18-14(26)13(25)15(29-18)19(27)28/h2-6,8-10,13-15,18,25-26H,7H2,1H3,(H,27,28)(H,20,21,23)/t10-,13-,14+,15-,18+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.30E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452321
PNG
(CHEMBL2093997)
Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H](CC)Cc3ccccc3)ncnc12
Show InChI InChI=1S/C22H28N6O4/c1-3-14(10-13-8-6-5-7-9-13)27-19-15-20(25-11-24-19)28(12-26-15)22-17(30)16(29)18(32-22)21(31)23-4-2/h5-9,11-12,14,16-18,22,29-30H,3-4,10H2,1-2H3,(H,23,31)(H,24,25,27)/t14-,16-,17+,18-,22+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.60E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50452314
PNG
(CHEMBL2094082)
Show SMILES CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H](C)Cc3ccccc3)ncnc12
Show InChI InChI=1S/C21H26N6O4/c1-3-22-20(30)17-15(28)16(29)21(31-17)27-11-25-14-18(23-10-24-19(14)27)26-12(2)9-13-7-5-4-6-8-13/h4-8,10-12,15-17,21,28-29H,3,9H2,1-2H3,(H,22,30)(H,23,24,26)/t12-,15-,16+,17-,21+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.20E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367378
PNG
(CHEMBL603362)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC(C)C
Show InChI InChI=1S/C18H28N6O4/c1-5-10(6-2)23-15-11-16(20-7-19-15)24(8-21-11)18-13(26)12(25)14(28-18)17(27)22-9(3)4/h7-10,12-14,18,25-26H,5-6H2,1-4H3,(H,22,27)(H,19,20,23)/t12-,13+,14-,18?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.10E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367377
PNG
(CHEMBL606289)
Show SMILES CNc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C11H13N5O5/c1-12-8-4-9(14-2-13-8)16(3-15-4)10-6(18)5(17)7(21-10)11(19)20/h2-3,5-7,10,17-18H,1H3,(H,19,20)(H,12,13,14)/t5-,6+,7-,10?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.30E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367379
PNG
(CHEMBL605239)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC
Show InChI InChI=1S/C16H24N6O4/c1-4-8(5-2)21-13-9-14(19-6-18-13)22(7-20-9)16-11(24)10(23)12(26-16)15(25)17-3/h6-8,10-12,16,23-24H,4-5H2,1-3H3,(H,17,25)(H,18,19,21)/t10-,11+,12-,16?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.40E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367367
PNG
(CHEMBL603358)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NCC=C
Show InChI InChI=1S/C18H26N6O4/c1-4-7-19-17(27)14-12(25)13(26)18(28-14)24-9-22-11-15(20-8-21-16(11)24)23-10(5-2)6-3/h4,8-10,12-14,18,25-26H,1,5-7H2,2-3H3,(H,19,27)(H,20,21,23)/t12-,13+,14-,18?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 8.90E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367369
PNG
(CHEMBL605867)
Show SMILES CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC)ncnc12
Show InChI InChI=1S/C13H18N6O4/c1-3-15-12(22)9-7(20)8(21)13(23-9)19-5-18-6-10(14-2)16-4-17-11(6)19/h4-5,7-9,13,20-21H,3H2,1-2H3,(H,15,22)(H,14,16,17)/t7-,8+,9-,13?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.73E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367366
PNG
(CHEMBL606288)
Show SMILES CN(C)c1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O
Show InChI InChI=1S/C12H15N5O5/c1-16(2)9-5-10(14-3-13-9)17(4-15-5)11-7(19)6(18)8(22-11)12(20)21/h3-4,6-8,11,18-19H,1-2H3,(H,20,21)/t6-,7+,8-,11?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367384
PNG
(CHEMBL606504)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C22H28N6O4/c1-3-14(4-2)27-19-15-20(25-11-24-19)28(12-26-15)22-17(30)16(29)18(32-22)21(31)23-10-13-8-6-5-7-9-13/h5-9,11-12,14,16-18,22,29-30H,3-4,10H2,1-2H3,(H,23,31)(H,24,25,27)/t16-,17+,18-,22?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367363
PNG
(CHEMBL603573)
Show SMILES CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(ncnc12)N(C)C
Show InChI InChI=1S/C14H20N6O4/c1-4-15-13(23)10-8(21)9(22)14(24-10)20-6-18-7-11(19(2)3)16-5-17-12(7)20/h5-6,8-10,14,21-22H,4H2,1-3H3,(H,15,23)/t8-,9+,10-,14?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367370
PNG
(CHEMBL603359)
Show SMILES CCC(CC)NC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC(CC)CC)ncnc12
Show InChI InChI=1S/C20H32N6O4/c1-5-11(6-2)24-17-13-18(22-9-21-17)26(10-23-13)20-15(28)14(27)16(30-20)19(29)25-12(7-3)8-4/h9-12,14-16,20,27-28H,5-8H2,1-4H3,(H,25,29)(H,21,22,24)/t14-,15+,16-,20?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50025446
PNG
(CHEMBL604408)
Show SMILES O[C@H]1[C@@H](O)C(O[C@@H]1C(=O)N1CCCCC1)n1cnc2c(NN3CCCCC3)ncnc12
Show InChI InChI=1S/C28H48N2O2/c1-5-6-7-8-9-10-19-29-26(32)23-13-12-21-20-11-14-24-28(3,18-16-25(31)30(24)4)22(20)15-17-27(21,23)2/h20-24H,5-19H2,1-4H3,(H,29,32)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367371
PNG
(CHEMBL603360)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)N(C)C
Show InChI InChI=1S/C17H26N6O4/c1-5-9(6-2)21-14-10-15(19-7-18-14)23(8-20-10)17-12(25)11(24)13(27-17)16(26)22(3)4/h7-9,11-13,17,24-25H,5-6H2,1-4H3,(H,18,19,21)/t11-,12+,13-,17?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367372
PNG
(CHEMBL605029)
Show SMILES CCC(CC)Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)N(CC)CC
Show InChI InChI=1S/C19H30N6O4/c1-5-11(6-2)23-16-12-17(21-9-20-16)25(10-22-12)19-14(27)13(26)15(29-19)18(28)24(7-3)8-4/h9-11,13-15,19,26-27H,5-8H2,1-4H3,(H,20,21,23)/t13-,14+,15-,19?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair
Adenosine A2 receptor


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50367374
PNG
(CHEMBL606285)
Show SMILES CCCCN(C)C(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NC(CC)CC)ncnc12
Show InChI InChI=1S/C20H32N6O4/c1-5-8-9-25(4)19(29)16-14(27)15(28)20(30-16)26-11-23-13-17(21-10-22-18(13)26)24-12(6-2)7-3/h10-12,14-16,20,27-28H,5-9H2,1-4H3,(H,21,22,24)/t14-,15+,16-,20?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Potency against PC12 cell A2 adenosine receptor by adenylate cyclase activation


J Med Chem 29: 1683-9 (1986)


Article DOI: 10.1021/jm00159a020
BindingDB Entry DOI: 10.7270/Q2Z89D0F
More data for this
Ligand-Target Pair