Compile Data Set for Download or QSAR
Found 19 of ic50 for UniProtKB: P17597
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079602(2,5-Dichloro-N-(4,6-dimethyl-pyrimidin-2-yl)-benze...)
Show SMILES Cc1cc(C)nc(NS(=O)(=O)c2cc(Cl)ccc2Cl)n1
Show InChI InChI=1S/C12H11Cl2N3O2S/c1-7-5-8(2)16-12(15-7)17-20(18,19)11-6-9(13)3-4-10(11)14/h3-6H,1-2H3,(H,15,16,17)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079609(4-Fluoro-N-(4-methyl-pyrimidin-2-yl)-benzenesulfon...)
Show SMILES Cc1ccnc(NS(=O)(=O)c2ccc(F)cc2)n1
Show InChI InChI=1S/C11H10FN3O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,1H3,(H,13,14,15)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079603(4-Bromo-N-(4-methyl-pyrimidin-2-yl)-benzenesulfona...)
Show SMILES Cc1ccnc(NS(=O)(=O)c2ccc(Br)cc2)n1
Show InChI InChI=1S/C11H10BrN3O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,1H3,(H,13,14,15)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216782(CHEMBL291948)
Show SMILES Cc1cccc(c1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C13H12N2O4/c1-9-3-2-4-10(7-9)12(17)19-8-15-6-5-11(16)14-13(15)18/h2-7H,8H2,1H3,(H,14,16,18)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079607(2,5-Dichloro-N-thiazol-2-yl-benzenesulfonamide | C...)
Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1nccs1
Show InChI InChI=1S/C9H6Cl2N2O2S2/c10-6-1-2-7(11)8(5-6)17(14,15)13-9-12-3-4-16-9/h1-5H,(H,12,13)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079606(2,5-Dichloro-N-(4-methyl-pyrimidin-2-yl)-benzenesu...)
Show SMILES Cc1ccnc(NS(=O)(=O)c2cc(Cl)ccc2Cl)n1
Show InChI InChI=1S/C11H9Cl2N3O2S/c1-7-4-5-14-11(15-7)16-19(17,18)10-6-8(12)2-3-9(10)13/h2-6H,1H3,(H,14,15,16)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079608(CHEMBL293152 | N-(4-Chloro-6-methoxy-pyrimidin-2-y...)
Show SMILES COc1cc(Cl)nc(NS(=O)(=O)c2ccc(F)cc2)n1
Show InChI InChI=1S/C11H9ClFN3O3S/c1-19-10-6-9(12)14-11(15-10)16-20(17,18)8-4-2-7(13)3-5-8/h2-6H,1H3,(H,14,15,16)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079605(4-Fluoro-N-(5-methyl-pyridin-2-yl)-benzenesulfonam...)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(F)cc2)nc1
Show InChI InChI=1S/C12H11FN2O2S/c1-9-2-7-12(14-8-9)15-18(16,17)11-5-3-10(13)4-6-11/h2-8H,1H3,(H,14,15)
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216775(CHEMBL57654)
Show SMILES Brc1ccc(cc1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C12H9BrN2O4/c13-9-3-1-8(2-4-9)11(17)19-7-15-6-5-10(16)14-12(15)18/h1-6H,7H2,(H,14,16,18)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216778(CHEMBL57215)
Show SMILES Clc1ccc(cc1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C12H9ClN2O4/c13-9-3-1-8(2-4-9)11(17)19-7-15-6-5-10(16)14-12(15)18/h1-6H,7H2,(H,14,16,18)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216780(CHEMBL58352)
Show SMILES O=C(OCn1ccc(=O)[nH]c1=O)c1ccccc1
Show InChI InChI=1S/C12H10N2O4/c15-10-6-7-14(12(17)13-10)8-18-11(16)9-4-2-1-3-5-9/h1-7H,8H2,(H,13,15,17)
Affinity DataIC50: 2.08E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216774(CHEMBL58964)
Show SMILES Fc1ccc(cc1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C12H9FN2O4/c13-9-3-1-8(2-4-9)11(17)19-7-15-6-5-10(16)14-12(15)18/h1-6H,7H2,(H,14,16,18)
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216779(CHEMBL58200)
Show SMILES FC(F)(F)c1cc(Cl)c(C(=O)OCn2ccc(=O)[nH]c2=O)c(Cl)c1
Show InChI InChI=1S/C13H7Cl2F3N2O4/c14-7-3-6(13(16,17)18)4-8(15)10(7)11(22)24-5-20-2-1-9(21)19-12(20)23/h1-4H,5H2,(H,19,21,23)
Affinity DataIC50: 2.61E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216773(CHEMBL61025)
Show SMILES Ic1ccc(cc1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C12H9IN2O4/c13-9-3-1-8(2-4-9)11(17)19-7-15-6-5-10(16)14-12(15)18/h1-6H,7H2,(H,14,16,18)
Affinity DataIC50: 2.69E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079601(CHEMBL293269 | N-(4-Methyl-pyrimidin-2-yl)-2-nitro...)
Show SMILES Cc1ccnc(NS(=O)(=O)c2ccccc2[N+]([O-])=O)n1
Show InChI InChI=1S/C11H10N4O4S/c1-8-6-7-12-11(13-8)14-20(18,19)10-5-3-2-4-9(10)15(16)17/h2-7H,1H3,(H,12,13,14)
Affinity DataIC50: 2.87E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50079604(2,5-Dichloro-N-(5-methyl-thiazol-2-yl)-benzenesulf...)
Show SMILES Cc1cnc(NS(=O)(=O)c2cc(Cl)ccc2Cl)s1
Show InChI InChI=1S/C10H8Cl2N2O2S2/c1-6-5-13-10(17-6)14-18(15,16)9-4-7(11)2-3-8(9)12/h2-5H,1H3,(H,13,14)
Affinity DataIC50: 3.09E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216781(CHEMBL58918)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C12H9N3O6/c16-10-5-6-14(12(18)13-10)7-21-11(17)8-1-3-9(4-2-8)15(19)20/h1-6H,7H2,(H,13,16,18)
Affinity DataIC50: 3.44E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216783(CHEMBL293995)
Show SMILES COc1ccc(cc1)C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C13H12N2O5/c1-19-10-4-2-9(3-5-10)12(17)20-8-15-7-6-11(16)14-13(15)18/h2-7H,8H2,1H3,(H,14,16,18)
Affinity DataIC50: 3.62E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50216776(CHEMBL58689)
Show SMILES COc1ccccc1C(=O)OCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C13H12N2O5/c1-19-10-5-3-2-4-9(10)12(17)20-8-15-7-6-11(16)14-13(15)18/h2-7H,8H2,1H3,(H,14,16,18)
Affinity DataIC50: 3.62E+5nMAssay Description:Inhibitory activity against Acetolactate synthase (ALS) enzyme by using the rape-root growth methodMore data for this Ligand-Target Pair