Compile Data Set for Download or QSAR
Found 41
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50300132(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
Affinity DataIC50: 130nMAssay Description:Inhibition of Agrobacterium tumefaciens TraRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50265814((S)-N-(2-oxotetrahydrofuran-3-yl)-3-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C14H14F3NO3/c15-14(16,17)10-4-1-9(2-5-10)3-6-12(19)18-11-7-8-21-13(11)20/h1-2,4-5,11H,3,6-8H2,(H,18,19)/t11-/m0/s1
Affinity DataIC50: 210nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50300131(CHEMBL575294 | N-(4-bromophenylacetanoyl)-L-homose...)
Show SMILES Brc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12BrNO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 250nMAssay Description:Inhibition of Agrobacterium tumefaciens TraRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266310((S)-2-(4-nitrophenoxy)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES [O-][N+](=O)c1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12N2O6/c15-11(13-10-5-6-19-12(10)16)7-20-9-3-1-8(2-4-9)14(17)18/h1-4,10H,5-7H2,(H,13,15)/t10-/m0/s1
Affinity DataIC50: 290nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266308((S)-2-(4-iodophenoxy)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES Ic1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12INO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 440nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266198((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)Oc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H12F3NO5/c14-13(15,16)22-9-3-1-8(2-4-9)21-7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
Affinity DataIC50: 460nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266198((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)Oc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H12F3NO5/c14-13(15,16)22-9-3-1-8(2-4-9)21-7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
Affinity DataIC50: 460nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50248862(CHEMBL473592 | N-(3-oxo-3-phenylpropanoyl)-L-homos...)
Show SMILES O=C(CC(=O)N[C@H]1CCOC1=O)Cc1ccccc1
Show InChI InChI=1S/C14H15NO4/c16-11(8-10-4-2-1-3-5-10)9-13(17)15-12-6-7-19-14(12)18/h1-5,12H,6-9H2,(H,15,17)/t12-/m0/s1
Affinity DataIC50: 500nMAssay Description:Inhibition of Agrobacterium tumefaciens TraRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266272((S)-2-(4-bromophenoxy)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES Brc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12BrNO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 510nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266271((S)-2-(4-chlorophenoxy)-N-(2-oxotetrahydrofuran-3-...)
Show SMILES Clc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12ClNO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 620nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50300132(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
Affinity DataIC50: 690nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50351508(CHEMBL259352)
Show SMILES CCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
Affinity DataIC50: 770nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
Affinity DataIC50: 810nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266165((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
Affinity DataIC50: 810nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50241433((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Show SMILES Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
Affinity DataIC50: 920nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50241433((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Show SMILES Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
Affinity DataIC50: 920nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50300130(CHEMBL573745 | N-(2-cyclopentene-1-acetanoyl)-L-ho...)
Show SMILES O=C(CC1CCC=C1)N[C@H]1CCOC1=O
Show InChI InChI=1S/C11H15NO3/c13-10(7-8-3-1-2-4-8)12-9-5-6-15-11(9)14/h1,3,8-9H,2,4-7H2,(H,12,13)/t8?,9-/m0/s1
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Agrobacterium tumefaciens TraRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50351509(CHEMBL8799)
Show SMILES CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50300133(CHEMBL573744 | N-(indole-3-butanoyl)-L-homoserine ...)
Show SMILES O=C(CCCc1c[nH]c2ccccc12)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H18N2O3/c19-15(18-14-8-9-21-16(14)20)7-3-4-11-10-17-13-6-2-1-5-12(11)13/h1-2,5-6,10,14,17H,3-4,7-9H2,(H,18,19)/t14-/m0/s1
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Agrobacterium tumefaciens TraRMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50265813((S)-3-(4-(methylthio)phenyl)-N-(2-oxotetrahydrofur...)
Show SMILES CSc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C14H17NO3S/c1-19-11-5-2-10(3-6-11)4-7-13(16)15-12-8-9-18-14(12)17/h2-3,5-6,12H,4,7-9H2,1H3,(H,15,16)/t12-/m0/s1
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266268((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(m-tolyloxy)ac...)
Show SMILES Cc1cccc(OCC(=O)N[C@H]2CCOC2=O)c1
Show InChI InChI=1S/C13H15NO4/c1-9-3-2-4-10(7-9)18-8-12(15)14-11-5-6-17-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266163((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266163((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens TraR receptor in presence of 100 nM 3-oxo-C8-HSLMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50265900((S)-3-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES [O-][N+](=O)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H14N2O5/c16-12(14-11-7-8-20-13(11)17)6-3-9-1-4-10(5-2-9)15(18)19/h1-2,4-5,11H,3,6-8H2,(H,14,16)/t11-/m0/s1
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266309((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H12F3NO4/c14-13(15,16)8-1-3-9(4-2-8)21-7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50350703(CHEMBL1814828)
Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCSC1=O
Show InChI InChI=1S/C16H27NO3S/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by b...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266267((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(p-tolyloxy)ac...)
Show SMILES Cc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H15NO4/c1-9-2-4-10(5-3-9)18-8-12(15)14-11-6-7-17-13(11)16/h2-5,11H,6-8H2,1H3,(H,14,15)/t11-/m0/s1
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50265811((S)-3-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H14INO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266164((S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES [O-][N+](=O)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12N2O5/c15-11(13-10-5-6-19-12(10)16)7-8-1-3-9(4-2-8)14(17)18/h1-4,10H,5-7H2,(H,13,15)/t10-/m0/s1
Affinity DataIC50: 2.25E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266237((S)-2-(3,4-dichlorophenyl)-N-(2-oxotetrahydrofuran...)
Show SMILES Clc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1Cl
Show InChI InChI=1S/C12H11Cl2NO3/c13-8-2-1-7(5-9(8)14)6-11(16)15-10-3-4-18-12(10)17/h1-2,5,10H,3-4,6H2,(H,15,16)/t10-/m0/s1
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266270((S)-2-(4-fluorophenoxy)-N-(2-oxotetrahydrofuran-3-...)
Show SMILES Fc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C12H12FNO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50350706(CHEMBL1811922)
Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCSC1=O
Show InChI InChI=1S/C16H29NO2S/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by b...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50350705(CHEMBL1814827)
Show SMILES CCCC(=O)CC(=O)N[C@H]1CCSC1=O
Show InChI InChI=1S/C10H15NO3S/c1-2-3-7(12)6-9(13)11-8-4-5-15-10(8)14/h8H,2-6H2,1H3,(H,11,13)/t8-/m0/s1
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by b...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50265809((S)-3-(4-chlorophenyl)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES Clc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H14ClNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266238((S)-2-(naphthalen-2-yl)-N-(2-oxotetrahydrofuran-3-...)
Show SMILES O=C(Cc1ccc2ccccc2c1)N[C@H]1CCOC1=O
Show InChI InChI=1S/C16H15NO3/c18-15(17-14-7-8-20-16(14)19)10-11-5-6-12-3-1-2-4-13(12)9-11/h1-6,9,14H,7-8,10H2,(H,17,18)/t14-/m0/s1
Affinity DataIC50: 4.20E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266269((S)-2-(4-methoxyphenoxy)-N-(2-oxotetrahydrofuran-3...)
Show SMILES COc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H15NO5/c1-17-9-2-4-10(5-3-9)19-8-12(15)14-11-6-7-18-13(11)16/h2-5,11H,6-8H2,1H3,(H,14,15)/t11-/m0/s1
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266234((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)Sc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H12F3NO3S/c14-13(15,16)21-9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
Affinity DataIC50: 4.70E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50266203((S)-2-(4-(methylthio)phenyl)-N-(2-oxotetrahydrofur...)
Show SMILES CSc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1
Show InChI InChI=1S/C13H15NO3S/c1-18-10-4-2-9(3-5-10)8-12(15)14-11-6-7-17-13(11)16/h2-5,11H,6-8H2,1H3,(H,14,15)/t11-/m0/s1
Affinity DataIC50: 8.40E+3nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF47 TraR receptor assessed as inhibition of OOHL-induced response by beta-galctosidase reporter ge...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50350708(CHEMBL1814832)
Show SMILES CCCCCCC(=O)N[C@H]1CCSC1=O
Show InChI InChI=1S/C11H19NO2S/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by b...More data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50241431((S)-2-(3-nitrophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Show SMILES [O-][N+](=O)c1cccc(CC(=O)N[C@H]2CCOC2=O)c1
Show InChI InChI=1S/C12H12N2O5/c15-11(13-10-4-5-19-12(10)16)7-8-2-1-3-9(6-8)14(17)18/h1-3,6,10H,4-5,7H2,(H,13,15)/t10-/m0/s1
Affinity DataEC50:  200nMAssay Description:Agonist activity at Agrobacterium tumefaciens WCF47 TraR receptor by beta-galctosidase reporter gene assayMore data for this Ligand-Target Pair
TargetTranscriptional activator protein TraR(Rhizobium radiobacter)
Universidad de Cartagena-Facultad de Ciencias Exactas y

Curated by ChEMBL
LigandPNGBDBM50350704(CHEMBL1814829)
Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCSC1=O
Show InChI InChI=1S/C12H19NO3S/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at Agrobacterium tumefaciens WCF (pCF372) TraR after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHLMore data for this Ligand-Target Pair