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Found 2861 of ic50 for UniProtKB: A0A0M3M0G7
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587715(CHEMBL5202283)
Affinity DataIC50:  0nMAssay Description:Inhibition of His-tagged PD-1/PD-L1 interaction (unknown origin) incubated for 1 to 4 hrs by HTRF binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50507505(CHEMBL4529967)
Affinity DataIC50:  0nMAssay Description:Inhibition of recombinant human PD1 (25 to 167 residues)/human PDL1 (19 to 238 residues) interaction after 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM491037((S)—N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(p...)
Affinity DataIC50: <0.000100nMAssay Description:In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Princip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death protein 1(Homo sapiens)
Institute Of Materia Medica, Chinese Academy Of Medical Sciences

US Patent
LigandPNGBDBM491057(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(pyrid...)
Affinity DataIC50:  0.000500nMAssay Description:In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Princip...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM575561(N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis...)
Affinity DataIC50:  0.0320nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM575599((1s,1's,3s,3's)-3,3'-((((((2,2'- dimethyl-[1,1'-bi...)
Affinity DataIC50:  0.0340nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM575553(N,N'-(2,2'-dimethyl-[1,1'-biphenyl]- 3,3'-diyl)bis...)
Affinity DataIC50:  0.0400nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50587714(CHEMBL5182195)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) by HTRF binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50567288(CHEMBL4865838)
Affinity DataIC50:  0.0510nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50567287(CHEMBL4862360)
Affinity DataIC50:  0.0580nMAssay Description:Inhibition of PD1/PD-L1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452113(US10710986, Example 252 | US11555029, No. 252)
Affinity DataIC50:  0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452008(US10710986, Example 148 | US11555029, No. 148)
Affinity DataIC50:  0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452150(US10710986, Example 289 | US11555029, No. 289)
Affinity DataIC50:  0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451887(US10710986, Example 26 | US11555029, No. 26)
Affinity DataIC50:  0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452147(US10710986, Example 286 | US11555029, No. 286)
Affinity DataIC50:  0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452007(US10710986, Example 147 | US11555029, No. 147)
Affinity DataIC50:  0.0600nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452136(US10710986, Example 275 | US11555029, No. 275)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452017(US10710986, Example 157 | US11555029, No. 157)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452055(US10710986, Example 195 | US11555029, No. 195)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451938(US10710986, Example 78 | US11555029, No. 78)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451974(US10710986, Example 114 | US11555029, No. 114)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451976(US10710986, Example 116 | US11555029, No. 116)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451981(US10710986, Example 121 | US11555029, No. 121)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451987(US10710986, Example 127 | US11555029, No. 127)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451989(US10710986, Example 129 | US11555029, No. 129)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451993(US10710986, Example 133 | US11555029, No. 133)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451994(US10710986, Example 134 | US11555029, No. 134)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452001(US10710986, Example 141 | US11555029, No. 141)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM451906(US10710986, Example 45 | US11555029, No. 45)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM575483(US11459339, Example 2 | US11459339, Example 4)
Affinity DataIC50:  0.0640nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452482(US10710986, Example 623 | US11555029, No. 623)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452485(US10710986, Example 626 | US11555029, No. 626)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452487(US10710986, Example 628 | US11555029, No. 628)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452490(US10710986, Example 631 | US11555029, No. 631)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452492(US10710986, Example 633 | US11555029, No. 633)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452493(US10710986, Example 634 | US11555029, No. 634)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452500(US10710986, Example 641 | US11555029, No. 641)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452501(US10710986, Example 642 | US11555029, No. 642)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452502(US10710986, Example 643 | US11555029, No. 643)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452504(US10710986, Example 645 | US11555029, No. 645)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452505(US10710986, Example 646 | US11555029, No. 646)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452506(US10710986, Example 647 | US11555029, No. 647)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452509(US10710986, Example 650 | US11555029, No. 650)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452510(US10710986, Example 651 | US11555029, No. 651)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452512(US10710986, Example 653 | US11555029, No. 653)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452514(US10710986, Example 655 | US11555029, No. 655)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452516(US10710986, Example 657 | US11555029, No. 657)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452520(US10710986, Example 661 | US11555029, No. 661)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452417(US10710986, Example 558 | US11555029, No. 558)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM452426(US10710986, Example 567 | US11555029, No. 567)
Affinity DataIC50:  0.0640nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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