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Found 10 of ic50 data for polymerid = 5288
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261586(CHEMBL4099180)
Affinity DataIC50:  60nMAssay Description:Inhibition of human CYP27B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261589(CHEMBL4081152)
Affinity DataIC50:  95nMAssay Description:Inhibition of human CYP27B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)
Affinity DataIC50:  340nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261588(CHEMBL4074768)
Affinity DataIC50:  410nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50214607(CHEMBL541423 | MK-24 | MK-24(S)-S(O)(NH)Ph)
Affinity DataIC50:  554nMAssay Description:Inhibition of CYP27B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50:  554nMAssay Description:Inhibition of human CYP27B hydroxylase expressed in SW900 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50556038(CHEMBL389014)
Affinity DataIC50:  554nMAssay Description:Inhibition of CYP27B in human SW900 cells using 3H-(23,24)-25-(OH)D3 as substrate incubated for 5 hrs by HPLC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50261587(CHEMBL4104395)
Affinity DataIC50:  570nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50214606(4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1...)
Affinity DataIC50:  616nMAssay Description:Inhibition of CYP27B1 in human keratinocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50322358(4'-Chloro-biphenyl-4-carboxylic acid((R)-2-imidazo...)
Affinity DataIC50:  616nMAssay Description:Inhibition of human CYP27B1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed