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Found 77 of ec50 for UniProtKB: A0A024R0J1
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101479(US8524710, 56 | US8530652, 50 | US8530652, 6)
Affinity DataKi:  2.80nM EC50:  0.940nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389123(CHEMBL2064631)
Affinity DataEC50:  1nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101543(US8530494, 206 | US8530652, 122 | US8530652, 70)
Affinity DataKi:  8.80nM EC50:  1.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101532(US8530494, 201 | US8530652, 110 | US8530652, 59)
Affinity DataKi:  170nM EC50:  2.40nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101530(US8530494, 29 | US8530494, 7 | US8530652, 57)
Affinity DataKi:  14nM EC50:  2.5nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101542(US8530494, 207 | US8530652, 121 | US8530652, 69)
Affinity DataKi:  1.90nM EC50:  3nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101546(US8530494, 211 | US8530652, 125 | US8530652, 73)
Affinity DataKi:  1.60nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101537(US8530494, 204 | US8530652, 115 | US8530652, 64)
Affinity DataKi:  3nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101547(US8530494, 212 | US8530652, 126 | US8530652, 74)
Affinity DataKi:  3.60nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101548(US8530494, 108 | US8530652, 127 | US8530652, 75)
Affinity DataKi:  5.20nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101549(US8530494, 109 | US8530652, 128 | US8530652, 76)
Affinity DataKi:  8.30nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101536(CHEMBL3128043 | US8530494, 203 | US8530652, 114 | ...)
Affinity DataKi:  20nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101552(US8530494, 214 | US8530652, 131 | US8530652, 79)
Affinity DataKi:  39nM EC50: >3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101533(US8530494, 103 | US8530652, 111 | US8530652, 60)
Affinity DataKi:  40nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101539(US8530494, 106 | US8530652, 117 | US8530652, 66)
Affinity DataKi:  170nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataEC50:  4nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101545(US8530494, 107 | US8530652, 124 | US8530652, 72)
Affinity DataKi:  16nM EC50:  4.40nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389108(CHEMBL2064632)
Affinity DataEC50:  7nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389117(CHEMBL2064562)
Affinity DataEC50:  9nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389116(CHEMBL2064561)
Affinity DataEC50:  11nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389111(CHEMBL2064555)
Affinity DataEC50:  12.6nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101535(US8530494, 104 | US8530652, 113 | US8530652, 62)
Affinity DataKi:  15nM EC50:  15nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389119(CHEMBL2064564)
Affinity DataEC50:  15nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101476(US8524710, 53 | US8530652, 3 | US8530652, 47)
Affinity DataKi:  11nM EC50:  16nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389122(CHEMBL2064629)
Affinity DataEC50:  16nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389110(CHEMBL2064630)
Affinity DataEC50:  18nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM4838(US8524710, 83 | US8530494, 13 | US8530652, 52)
Affinity DataKi:  3.5nM EC50:  19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM4838(US8524710, 83 | US8530494, 13 | US8530652, 52)
Affinity DataKi:  3.5nM EC50:  19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101534(US8530494, 202 | US8530652, 112 | US8530652, 61)
Affinity DataKi:  22nM EC50:  19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101541(US8530494, 104 | US8530652, 120 | US8530652, 68)
Affinity DataKi:  6.70nM EC50:  20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101553(US8530494, 215 | US8530652, 132 | US8530652, 80)
Affinity DataKi:  120nM EC50:  20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101540(US8530494, 205 | US8530652, 118 | US8530652, 67)
Affinity DataKi:  280nM EC50:  20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101504(US8524699, 91 | US8524710, 82 | US8530652, 31)
Affinity DataKi:  7.20nM EC50:  21nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389115(CHEMBL2064560)
Affinity DataEC50:  21nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389120(CHEMBL2064565)
Affinity DataEC50:  28nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101524(US8530652, 51 | US8530652, 96)
Affinity DataKi:  18nM EC50:  31nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101518(US8524699, 46 | US8530652, 45 | US8530652, 90)
Affinity DataKi:  25nM EC50:  32nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389113(CHEMBL2064558)
Affinity DataEC50:  32nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101475(US8524710, 52 | US8530652, 2 | US8530652, 46)
Affinity DataKi:  14nM EC50:  36nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM50389118(CHEMBL2064563)
Affinity DataEC50:  36nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101538(US8530494, 208 | US8530652, 116 | US8530652, 65)
Affinity DataKi:  680nM EC50:  67.1nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101550(US8530494, 110 | US8530652, 129 | US8530652, 77)
Affinity DataKi:  93nM EC50:  69nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101485(US8524710, 62 | US8530652, 12 | US8530652, 56)
Affinity DataKi:  38nM EC50:  78nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101638(US8530652, 83)
Affinity DataKi:  58nM EC50:  84nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101478(US8524710, 55 | US8530652, 49 | US8530652, 5)
Affinity DataKi:  220nM EC50:  87nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101513(US8524699, 18 | US8530652, 40 | US8530652, 85)
Affinity DataKi:  18nM EC50:  98nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101504(US8524699, 91 | US8524710, 82 | US8530652, 31)
Affinity DataKi:  20nM EC50:  103nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101514(US8524699, 22 | US8530652, 41 | US8530652, 86)
Affinity DataKi:  24nM EC50:  147nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101508(US8524710, 87 | US8530652, 35 | US8530652, 80)
Affinity DataKi:  260nM EC50:  262nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals

US Patent
LigandPNGBDBM101522(US8530652, 49 | US8530652, 94 | US8530670, 4)
Affinity DataKi:  160nM EC50:  332nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
In DepthDetails US Patent
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