Affinity DataIC50: <0.150nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] by Hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Binding affinity to LYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of recombinant human Lyn using peptide substrate poly[Glu:Tyr] (4:1) in presence of [33-P]ATP by kinase hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMT: 2°CAssay Description:Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Lyn (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.473nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >0.5nMAssay Description:Inhibition of Lyn kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.728nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.805nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.964nMAssay Description:Inhibition of human LYN-B using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of Lyn (unknown origin) after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 uM ATP.). Reaction condition...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.20nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human LynMore data for this Ligand-Target Pair
Affinity DataIC50: 1.39nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55nMAssay Description:Inhibition of LYN-A expressed in Sf9 cells after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human LYN using poly(Glu,Tyr)4:1 substrate and [gamma-33P]-ATP incubated for 40 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Protein tyrosine kinase LynMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of LYNA (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human LYN-B using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human full length recombinant LYN using poly(Glu,Tyr)4:1 as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometri...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of LYNA (unknown origin) after 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human full length recombinant LYN by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human full length recombinant LYN by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
