BindingDB PrimarySearch_ki

Found 243 of ic50 for UniProtKB: Q9R1E6

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50187693(CHEMBL3186509)

IC50: 1.70nMAssay Description:Inhibition of recombinant mouse ATX expressed in HEK293 cells using LPC 17:0 as substrate after 30 mins by LC-MS/MS methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50187693(CHEMBL3186509)

IC50: 2.80nMAssay Description:Inhibition of recombinant mouse ATX expressed in HEK293 cells using FS3 as substrate preincubated for 15 mins followed by substrate addition measured...More data for this Ligand-Target Pair

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3D Structure (crystal)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527415(CHEMBL4529959)

IC50: 3.30nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM369940((R)—N-(1-(1-(1H-indazol-5-yl)-3-methyl-2,4-di...)

IC50: 7nMAssay Description:Inhibition of autotaxin in mouse plasma assessed as reduction in LPA (18:2) production incubated for 2 hrs LC-MS-/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527451(CHEMBL4515130)

IC50: 9.40nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527434(CHEMBL4466454)

IC50: 9.90nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527442(CHEMBL4465067)

IC50: 11nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50266936(CHEMBL4078601)

IC50: 13nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527449(CHEMBL4442653)

IC50: 13nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM103575(ATX inhibitor 10 analogue 5 | US8551988, 65)

IC50: 13nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527429(CHEMBL4593078)

IC50: 14nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527459(CHEMBL4581989)

IC50: 15nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527435(CHEMBL4474913)

IC50: 16nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527445(CHEMBL4453366)

IC50: 19nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50266937(CHEMBL4095125)

IC50: 20nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527452(CHEMBL4451331)

IC50: 21nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM103576(ATX inhibitor 10 analogue 6)

IC50: 22nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527412(CHEMBL4482895)

IC50: 23nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM103577(ATX inhibitor 10 analogue 7)

IC50: 25nMMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM103568(ATX inhibitor 16 | Chicago Sky Blue)

IC50: 26nMMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527440(CHEMBL4469815)

IC50: 26nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527444(CHEMBL4438238)

IC50: 30nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527439(CHEMBL4471030)

IC50: 31nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527427(CHEMBL4572641)

IC50: 31nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527443(CHEMBL4534048)

IC50: 37nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527433(CHEMBL4515759)

IC50: 40nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527432(CHEMBL4474496)

IC50: 44nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM103980(Disubstituted aryl-Me ATX inhibitor 8)

IC50: 45nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50527458(CHEMBL4535941)

IC50: 49nMAssay Description:Inhibition of ATX in mouse plasma after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM50264197(CHEMBL4094633)

IC50: 50nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM103979(Disubstituted aryl-Me ATX inhibitor 7)

IC50: 53nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354337(2-((6-(4-(2- (azetidin-1-yl)-2- oxoethyl)piperazin...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354338(2-(4-(3-((5-cyano- 4-(4- fluorophenyl) thiazol-2- ...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354339((R)-2-((2-ethyl-6- (4-(2-(3- hydroxypyrrolidin- 1-...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354340((S)-2-((2-ethyl-6- (4-(2-(3- hydroxypyrrolidin- 1-...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354341(2-((2-ethyl-6-(4-(2- oxo-2-(pyrrolidin- 1- yl)ethy...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354342(2-(4-(3-((5-cyano- 4-(4- fluorophenyl) thiazol-2- ...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354343(2-((2-ethyl-6-(4-(2- morpholino-2- oxoethyl)pipera...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354344(2-((2-ethyl-6-(4-(2- (3-fluoroazetidin-1- yl)-2- o...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354345(2-((2-ethyl-6-(4-(2- (3-hydroxyazetidin- 1-yl)acet...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354353(2-((2-ethyl-6-(1-(2- (3-hydroxyazetidin- 1-yl)-2-o...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354355(2-((2-ethyl-6-(1-(2- (3-hydroxyazetidin- 1-yl)-2- ...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354356((R)-2-((2-ethyl-6- (1-(2-(3- hydroxypyrrolidin- 1-...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354357((S)-2-((2-ethyl-6- (1-(2-(3- hydroxypyrrolidin- 1-...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354358(2-(4-(2-ethyl-3-((4- (4- fluorophenl) thiazol-2- y...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Details US Patent

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354359(2-((2-ethyl-6-(4-(2- (3-hydroxyazetidin- 1-yl)-2- ...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Details US Patent

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354361(2-(4-(2-ethyl-3-((4- (4- fluorophenyl) thiazol-2- ...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Details US Patent

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354365((R)-2-(4-(2-ethyl-3- ((4-(4- fluorophenyl) thiazol...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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Details US Patent

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354366((S)-2-(4-(2-ethyl-3- ((4-(4- fluorophenyl) thiazol...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Details US Patent

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National And Kapodistrian University Of Athens

Curated by ChEMBL

PNG

BDBM354372(5-((4-(2-ethyl-3- ((4-(4- fluorophenyl) thiazol-2-...)

IC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair

PDB MMDB KEGG
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Details US Patent

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