Compile Data Set for Download or QSAR
maximum 50k data
Found 244 of ic50 for UniProtKB: P05622
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446312(CHEMBL3109350)
Affinity DataIC50:  1nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446319(CHEMBL3109343)
Affinity DataIC50:  1nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446315(CHEMBL3109347)
Affinity DataIC50:  2nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Platelet-derived growth factor receptor in P19 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50384726(CHEMBL2037208)
Affinity DataIC50:  2nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446303(CHEMBL3109338)
Affinity DataIC50:  3nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446306(CHEMBL3109340)
Affinity DataIC50:  3nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446316(CHEMBL3109346)
Affinity DataIC50:  3nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446305(CHEMBL3109356)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  4nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446318(CHEMBL3109344)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50185169(2-(5-phenoxy-1H-indazol-3-yl)-5-(4-(piperidin-1-yl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446321(CHEMBL3109341)
Affinity DataIC50:  9nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446311(CHEMBL3109351)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181306(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446322(CHEMBL3109339)
Affinity DataIC50:  18nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446306(CHEMBL3109340)
Affinity DataIC50:  25nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446305(CHEMBL3109356)
Affinity DataIC50:  25nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181314(4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)quinolin-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181320(4-Amino-3-[6-(4-methylpiperazinyl)benzimidazol-2-y...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446314(CHEMBL3109348)
Affinity DataIC50:  28nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446312(CHEMBL3109350)
Affinity DataIC50:  29nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181315(4-amino-3-(5-(4-methylpiperazin-1-yl)-3H-imidazo[4...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446320(CHEMBL3109342)
Affinity DataIC50:  34nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181311(4-Amino-3-(6-morpholin-4-ylbenzimidazol-2-yl)hydro...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181308(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181312(4-amino-3-(5-morpholino-3H-imidazo[4,5-b]pyridin-2...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181303(4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naph...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181307(4-amino-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]i...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446303(CHEMBL3109338)
Affinity DataIC50:  55nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  57nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181313(4-amino-3-(1H-benzo[d]imidazol-2-yl)-1,7-naphthyri...)
Affinity DataIC50:  57nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50185181(5-(4-(piperidin-1-yl)piperidin-1-yl)-2-(6-(trifluo...)
Affinity DataIC50:  62nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50185183(CHEMBL380372 | methyl 3-(5-(4-(piperidin-1-yl)pipe...)
Affinity DataIC50:  63nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181319(4-amino-3-(6-morpholino-1H-benzo[d]imidazol-2-yl)-...)
Affinity DataIC50:  64nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  70nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446304(CHEMBL3109337)
Affinity DataIC50:  70nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM3104(2-(4-{[6-(2,6-dichlorophenyl)-8-methyl-7-oxo-7H,8H...)
Affinity DataIC50:  70nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50:  70nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) in human aortic smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50446317(CHEMBL3109345)
Affinity DataIC50:  72nMAssay Description:Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50185178(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  81nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  83nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataIC50:  85nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM3096(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. | 6...)
Affinity DataIC50:  96nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50279588(CHEMBL4170680)
Affinity DataIC50:  97nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50279591(CHEMBL4172155)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50279593(CHEMBL4168811)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50384725(CHEMBL2037209)
Affinity DataIC50:  100nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50181305(4-amino-3-(1H-benzo[d]imidazol-2-yl)quinolin-2(1H)...)
Affinity DataIC50:  102nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 244 total ) | Next | Last >>
Jump to: