Compile Data Set for Download or QSAR

Found 101 hits for UniProtKB: Q9NQS7   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora B/Incenp (Homo sapiens (Human))	BDBM209861 (5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...) Show SMILES CCS(=O)(=O)c1cccc(c1)-c1cc(C(=O)NC2CCN(C)CC2)c(C)c2[nH]c3ncc(C)cc3c12 Show InChI InChI=1S/C28H32N4O3S/c1-5-36(34,35)21-8-6-7-19(14-21)23-15-22(28(33)30-20-9-11-32(4)12-10-20)18(3)26-25(23)24-13-17(2)16-29-27(24)31-26/h6-8,13-16,20H,5,9-12H2,1-4H3,(H,29,31)(H,30,33)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of Aurora B/INCENP (unknown origin) assessed as affinity constant pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP addition				Eur J Med Chem 140: 1-19 (2017) BindingDB Entry DOI: 10.7270/Q2WD4385
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50315769 (3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...) Show SMILES CCn1cc(c(n1)-c1ccc(NC(=O)N(C)C)cc1)-c1ccnc2[nH]c(cc12)-c1cccc(CN(C)C)c1 Show InChI InChI=1S/C30H33N7O/c1-6-37-19-26(28(34-37)21-10-12-23(13-11-21)32-30(38)36(4)5)24-14-15-31-29-25(24)17-27(33-29)22-9-7-8-20(16-22)18-35(2)3/h7-17,19H,6,18H2,1-5H3,(H,31,33)(H,32,38)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of human Aurora B/INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 120 mins				Eur J Med Chem 140: 1-19 (2017) BindingDB Entry DOI: 10.7270/Q2WD4385
					More data for this Ligand-Target Pair
Aurora-C/INCENP (Homo sapiens (Human))	BDBM50315769 (3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...) Show SMILES CCn1cc(c(n1)-c1ccc(NC(=O)N(C)C)cc1)-c1ccnc2[nH]c(cc12)-c1cccc(CN(C)C)c1 Show InChI InChI=1S/C30H33N7O/c1-6-37-19-26(28(34-37)21-10-12-23(13-11-21)32-30(38)36(4)5)24-14-15-31-29-25(24)17-27(33-29)22-9-7-8-20(16-22)18-35(2)3/h7-17,19H,6,18H2,1-5H3,(H,31,33)(H,32,38)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of human Aurora C/human GST-tagged INCENP pre-incubated for 30 mins before 5-FAM-PKAtide substrate addition and measured after 60 mins				Eur J Med Chem 140: 1-19 (2017) BindingDB Entry DOI: 10.7270/Q2WD4385
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465482 (CHEMBL4288628) Show SMILES Cn1cc(cn1)-c1c[nH]c(=O)c(N)c1 Show InChI InChI=1S/C9H10N4O/c1-13-5-7(4-12-13)6-2-8(10)9(14)11-3-6/h2-5H,10H2,1H3,(H,11,14)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465481 (CHEMBL4291472) Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccnc(NC2CC2)n1)c1ccccc1 Show InChI InChI=1S/C19H17N5O2/c25-17(12-4-2-1-3-5-12)23-16-10-13(11-21-18(16)26)15-8-9-20-19(24-15)22-14-6-7-14/h1-5,8-11,14H,6-7H2,(H,21,26)(H,23,25)(H,20,22,24)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465478 (CHEMBL4286130) Show SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C22H23N5O2/c1-26-10-12-27(13-11-26)19-4-2-17(3-5-19)21(28)25-20-14-18(15-24-22(20)29)16-6-8-23-9-7-16/h2-9,14-15H,10-13H2,1H3,(H,24,29)(H,25,28)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50341520 (3-(4-(Piperidin-1-yl)benzoylamino)-5-(pyridin-4-yl...) Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)c1ccc(cc1)N1CCCCC1 Show InChI InChI=1S/C22H22N4O2/c27-21(17-4-6-19(7-5-17)26-12-2-1-3-13-26)25-20-14-18(15-24-22(20)28)16-8-10-23-11-9-16/h4-11,14-15H,1-3,12-13H2,(H,24,28)(H,25,27)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465486 (CHEMBL4282263) Show SMILES Nc1cc(c[nH]c1=O)-c1ccnc(NC2CC2)n1 Show InChI InChI=1S/C12H13N5O/c13-9-5-7(6-15-11(9)18)10-3-4-14-12(17-10)16-8-1-2-8/h3-6,8H,1-2,13H2,(H,15,18)(H,14,16,17)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465490 (CHEMBL4280041) Show SMILES CN(C)Cc1ccc(cc1)-c1c[nH]c(=O)c(N)c1 Show InChI InChI=1S/C14H17N3O/c1-17(2)9-10-3-5-11(6-4-10)12-7-13(15)14(18)16-8-12/h3-8H,9,15H2,1-2H3,(H,16,18)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465485 (CHEMBL4292538) Show SMILES CNc1nccc(n1)-c1c[nH]c(=O)c(N)c1 Show InChI InChI=1S/C10H11N5O/c1-12-10-13-3-2-8(15-10)6-4-7(11)9(16)14-5-6/h2-5H,11H2,1H3,(H,14,16)(H,12,13,15)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465488 (CHEMBL4295011) Show SMILES Nc1cc(c[nH]c1=O)-c1cncnc1 Show InChI InChI=1S/C9H8N4O/c10-8-1-6(4-13-9(8)14)7-2-11-5-12-3-7/h1-5H,10H2,(H,13,14)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50226223 (CHEMBL302219) Show SMILES Cc1nc(O)c(N)cc1-c1ccncc1 Show InChI InChI=1S/C11H11N3O/c1-7-9(6-10(12)11(15)14-7)8-2-4-13-5-3-8/h2-6H,12H2,1H3,(H,14,15)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465492 (CHEMBL4292942) Show SMILES COc1cc(OC)cc(c1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C19H17N3O4/c1-25-15-7-13(8-16(10-15)26-2)18(23)22-17-9-14(11-21-19(17)24)12-3-5-20-6-4-12/h3-11H,1-2H3,(H,21,24)(H,22,23)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	3.29E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50341532 (3-Benzoylamino-5-(pyridin-4-yl)-(1H)-pyridin-2-one...) Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C17H13N3O2/c21-16(13-4-2-1-3-5-13)20-15-10-14(11-19-17(15)22)12-6-8-18-9-7-12/h1-11H,(H,19,22)(H,20,21)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465484 (CHEMBL4280308) Show SMILES Nc1cc(c[nH]c1=O)-c1ccnc2ccccc12 Show InChI InChI=1S/C14H11N3O/c15-12-7-9(8-17-14(12)18)10-5-6-16-13-4-2-1-3-11(10)13/h1-8H,15H2,(H,17,18)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	4.17E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM34651 (Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...) Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents	PubMed	5.93E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465483 (CHEMBL4291350) Show SMILES COc1ncc(cc1N)-c1ccncc1 Show InChI InChI=1S/C11H11N3O/c1-15-11-10(12)6-9(7-14-11)8-2-4-13-5-3-8/h2-7H,12H2,1H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	6.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465487 (CHEMBL1605269) Show SMILES Nc1cc(cnc1O)-c1ccccc1 Show InChI InChI=1S/C11H10N2O/c12-10-6-9(7-13-11(10)14)8-4-2-1-3-5-8/h1-7H,12H2,(H,13,14)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	7.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465489 (CHEMBL1201292) Show SMILES Nc1cc(c[nH]c1=O)-c1cccnc1 Show InChI InChI=1S/C10H9N3O/c11-9-4-8(6-13-10(9)14)7-2-1-3-12-5-7/h1-6H,11H2,(H,13,14)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	9.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465495 (CHEMBL4278218) Show SMILES O=c1[nH]cc(cc1NS(=O)(=O)c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C16H13N3O3S/c20-16-15(19-23(21,22)14-4-2-1-3-5-14)10-13(11-18-16)12-6-8-17-9-7-12/h1-11,19H,(H,18,20)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465477 (CHEMBL4285109) Show SMILES COc1cccc(c1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C18H15N3O3/c1-24-15-4-2-3-13(9-15)17(22)21-16-10-14(11-20-18(16)23)12-5-7-19-8-6-12/h2-11H,1H3,(H,20,23)(H,21,22)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465491 (CHEMBL4278538) Show SMILES Cc1[nH]c(=O)c(cc1-c1ccncc1)C(N)=O Show InChI InChI=1S/C12H11N3O2/c1-7-9(8-2-4-14-5-3-8)6-10(11(13)16)12(17)15-7/h2-6H,1H3,(H2,13,16)(H,15,17)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465494 (CHEMBL4279867) Show SMILES Fc1cc(F)cc(c1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C17H11F2N3O2/c18-13-5-11(6-14(19)8-13)16(23)22-15-7-12(9-21-17(15)24)10-1-3-20-4-2-10/h1-9H,(H,21,24)(H,22,23)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465493 (CHEMBL4281678) Show SMILES Fc1cccc(c1)C(=O)Nc1cc(c[nH]c1=O)-c1ccncc1 Show InChI InChI=1S/C17H12FN3O2/c18-14-3-1-2-12(8-14)16(22)21-15-9-13(10-20-17(15)23)11-4-6-19-7-5-11/h1-10H,(H,20,23)(H,21,22)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM15296 (6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...) Show SMILES Cc1[nH]c(=O)c(cc1-c1ccncc1)C#N Show InChI InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465480 (CHEMBL4282410) Show SMILES Cn1cc(cc(N)c1=O)-c1ccncc1 Show InChI InChI=1S/C11H11N3O/c1-14-7-9(6-10(12)11(14)15)8-2-4-13-5-3-8/h2-7H,12H2,1H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50465479 (CHEMBL4286709) Show SMILES Nc1ccc[nH]c1=O Show InChI InChI=1S/C5H6N2O/c6-4-2-1-3-7-5(4)8/h1-3H,6H2,(H,7,8)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...				Bioorg Med Chem 26: 3021-3029 (2018) BindingDB Entry DOI: 10.7270/Q2736TKN
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM47224 (US9073917, 2-inventive) Show SMILES CCc1[nH]cc2[C@@H](C3=C(CCCC3=O)Nc12)c1cccc(Oc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50277545 (4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...) Show SMILES COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O Show InChI InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11,13H,12H2,1-2H3,(H,34,35)(H,31,32,33)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50175305 (CHEMBL3600873) Show SMILES OC(=O)[C@@]1(Cc2cccc(Nc3nccs3)n2)CC[C@@H](CC1)Oc1cccc(Cl)c1F Show InChI InChI=1S/C22H21ClFN3O3S/c23-16-4-2-5-17(19(16)24)30-15-7-9-22(10-8-15,20(28)29)13-14-3-1-6-18(26-14)27-21-25-11-12-31-21/h1-6,11-12,15H,7-10,13H2,(H,28,29)(H,25,26,27)/t15-,22-	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167515 (US9073917, 12- comparative) Show SMILES CCOC(=O)c1[nH]cc2[C@@H](c3ccc(Sc4nc5ccccc5[nH]4)o3)C3=C(CCCC3=O)Nc12 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167506 (US9073917, 1-inventive) Show SMILES CCc1[nH]cc2C(C3=C(CCCC3=O)Nc12)c1cccc(Oc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167510 (US9073917, 7- comparative) Show SMILES CCc1[nH]cc2C(C3=C(CC(C)(C)CC3=O)Nc12)c1cccc(Oc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167507 (US9073917, 4- comparative) Show SMILES CCc1[nH]cc2C(C3=C(CCCC3=O)Nc12)c1cccc(Sc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167508 (US9073917, 5- comparative) Show SMILES O=C1CCCC2=C1C(c1c[nH]nc1N2)c1cccc(Oc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) Show SMILES CCc1[nH]cc2C(C3=C(CNCC3=O)Nc12)c1cccc(Sc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167513 (US9073917, 10- comparative) Show SMILES CC1(C)CC(=O)C2=C(C1)Nc1n[nH]cc1C2c1cccc(Oc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167516 (US9073917, 13- comparative) Show SMILES CCOC(=O)c1[nH]cc2C(c3ccc(Sc4nc5cccc(OC)c5[nH]4)o3)C3=C(CCCC3=O)Nc12 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167509 (US9073917, 6- comparative) Show SMILES O=C1CNCC2=C1C(c1c[nH]nc1N2)c1cccc(Oc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM209861 (5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...) Show SMILES CCS(=O)(=O)c1cccc(c1)-c1cc(C(=O)NC2CCN(C)CC2)c(C)c2[nH]c3ncc(C)cc3c12 Show InChI InChI=1S/C28H32N4O3S/c1-5-36(34,35)21-8-6-7-19(14-21)23-15-22(28(33)30-20-9-11-32(4)12-10-20)18(3)26-25(23)24-13-17(2)16-29-27(24)31-26/h6-8,13-16,20H,5,9-12H2,1-4H3,(H,29,31)(H,30,33)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Nirma University Curated by ChEMBL					Assay Description Inhibition of Aurora B/INCENP (unknown origin) pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP addition				Eur J Med Chem 140: 1-19 (2017) BindingDB Entry DOI: 10.7270/Q2WD4385
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50244953 (CHEMBL4063500) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 Show InChI InChI=1S/C28H37N7O4/c1-34(2)27(38)23-17-19-18-29-28(32-26(19)35(23)22-9-7-8-10-22)31-21-15-13-20(14-16-21)30-24(36)11-5-3-4-6-12-25(37)33-39/h13-18,22,39H,3-12H2,1-2H3,(H,30,36)(H,33,37)(H,29,31,32)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Nankai University Curated by ChEMBL					Assay Description Binding affinity towards [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in HG108-15				J Med Chem 61: 3166-3192 (2018) Article DOI: 10.1021/acs.jmedchem.8b00209 BindingDB Entry DOI: 10.7270/Q2KS6TZK
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167511 (US9073917, 8- comparative) Show SMILES CCc1[nH]cc2C(C3=C(CC(C)(C)CC3=O)Nc12)c1cccc(Sc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora-C/INCENP (Homo sapiens (Human))	BDBM50244953 (CHEMBL4063500) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 Show InChI InChI=1S/C28H37N7O4/c1-34(2)27(38)23-17-19-18-29-28(32-26(19)35(23)22-9-7-8-10-22)31-21-15-13-20(14-16-21)30-24(36)11-5-3-4-6-12-25(37)33-39/h13-18,22,39H,3-12H2,1-2H3,(H,30,36)(H,33,37)(H,29,31,32)	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Nankai University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged Aurora-C (35-end residues)/N-terminal GST-tagged INCENP (821-end residues) expressed in baculo...				J Med Chem 61: 3166-3192 (2018) Article DOI: 10.1021/acs.jmedchem.8b00209 BindingDB Entry DOI: 10.7270/Q2KS6TZK
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) Show SMILES CCc1[nH]cc2C(C3=C(CNCC3=O)Nc12)c1cccc(Sc2nc3ccccc3[nH]2)c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...				US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50198027 (CHEMBL3921246) Show SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(Nc3ccc(cn3)C(O)=O)c2)C(=O)N1C Show InChI InChI=1S/C24H21N5O3S/c1-3-15-4-7-18(8-5-15)27-24-29(2)22(30)19(33-24)12-16-10-11-25-21(13-16)28-20-9-6-17(14-26-20)23(31)32/h4-14H,3H2,1-2H3,(H,31,32)(H,25,26,28)/b19-12-,27-24-	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50467633 (CHEMBL4291945) Show SMILES Cc1ccnc(COc2ccc(C)nc2-c2ccc3CCNCCc3c2)c1 Show InChI InChI=1S/C23H25N3O/c1-16-7-12-25-21(13-16)15-27-22-6-3-17(2)26-23(22)20-5-4-18-8-10-24-11-9-19(18)14-20/h3-7,12-14,24H,8-11,15H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	PC cid PC sid UniChem	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...				Bioorg Med Chem Lett 28: 3458-3462 (2018) BindingDB Entry DOI: 10.7270/Q2X3515K
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50198044 (CHEMBL3903187) Show SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(Nc3ccc(cc3)-c3nnn[nH]3)c2)C(=O)N1C Show InChI InChI=1S/C25H22N8OS/c1-3-16-4-8-20(9-5-16)28-25-33(2)24(34)21(35-25)14-17-12-13-26-22(15-17)27-19-10-6-18(7-11-19)23-29-31-32-30-23/h4-15H,3H2,1-2H3,(H,26,27)(H,29,30,31,32)/b21-14-,28-25-	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50198086 (CHEMBL3985313) Show SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(NC(=O)CCCC(O)=O)c2)C(=O)N1C Show InChI InChI=1S/C23H24N4O4S/c1-3-15-7-9-17(10-8-15)25-23-27(2)22(31)18(32-23)13-16-11-12-24-19(14-16)26-20(28)5-4-6-21(29)30/h7-14H,3-6H2,1-2H3,(H,29,30)(H,24,26,28)/b18-13-,25-23-	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50198082 (CHEMBL3904239) Show SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(Nc3ccc(cc3)C(O)=O)c2)C(=O)N1C Show InChI InChI=1S/C25H22N4O3S/c1-3-16-4-8-20(9-5-16)28-25-29(2)23(30)21(33-25)14-17-12-13-26-22(15-17)27-19-10-6-18(7-11-19)24(31)32/h4-15H,3H2,1-2H3,(H,26,27)(H,31,32)/b21-14-,28-25-	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair
Aurora B/Incenp (Homo sapiens (Human))	BDBM50198081 (CHEMBL3915550) Show SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(NC(=O)CCC(O)=O)c2)C(=O)N1C Show InChI InChI=1S/C22H22N4O4S/c1-3-14-4-6-16(7-5-14)24-22-26(2)21(30)17(31-22)12-15-10-11-23-18(13-15)25-19(27)8-9-20(28)29/h4-7,10-13H,3,8-9H2,1-2H3,(H,28,29)(H,23,25,27)/b17-12-,24-22-	PDB Reactome pathway UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assay				J Med Chem 59: 7188-211 (2016) Article DOI: 10.1021/acs.jmedchem.6b00709 BindingDB Entry DOI: 10.7270/Q2JM2CM5
					More data for this Ligand-Target Pair

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