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Found 481 of ec50 for UniProtKB: P30679
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222990(US9315518, 34-3)
Affinity DataEC50:  14.4nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222972(US9315518, 2-7 | US9315518, 5-2)
Affinity DataEC50:  16.0nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222977(US9315518, 8-38)
Affinity DataEC50:  17.9nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222971(US9315518, 2-34)
Affinity DataEC50:  22.8nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222967(US9315518, 2-8)
Affinity DataEC50:  28.1nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222973(US9315518, 6-4)
Affinity DataEC50:  29.0nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222984(US9315518, 18-200)
Affinity DataEC50:  43.2nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222987(US9315518, 24-7)
Affinity DataEC50:  48.5nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222970(US9315518, 2-22)
Affinity DataEC50:  56.1nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222969(US9315518, 2-16)
Affinity DataEC50:  64.1nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222968(US9315518, 2-9)
Affinity DataEC50:  100nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222986(US9315518, 19-62)
Affinity DataEC50:  116nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222979(US9315518, 14-6)
Affinity DataEC50:  123nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222976(US9315518, 8-14)
Affinity DataEC50:  134nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222988(US9315518, 24-20)
Affinity DataEC50:  177nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222975(US9315518, 8-9)
Affinity DataEC50:  270nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222972(US9315518, 2-7 | US9315518, 5-2)
Affinity DataEC50:  322nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222981(US9315518, 17-20)
Affinity DataEC50:  333nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222989(US9315518, 25-5)
Affinity DataEC50:  359nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222978(US9315518, 11-5)
Affinity DataEC50:  391nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222974(US9315518, 8-6)
Affinity DataEC50:  513nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222980(US9315518, 17-15)
Affinity DataEC50:  594nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222985(US9315518, 19-4)
Affinity DataEC50:  951nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222983(US9315518, 18-42)
Affinity DataEC50:  986nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222991(US9315518, 38-5)
Affinity DataEC50:  1.18E+3nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM222982(US9315518, 18-10)
Affinity DataEC50:  2.19E+3nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96916(MLS001000420 | N-(diphenylmethyl)-3-(2-ethoxyethox...)
Affinity DataEC50:  1.03E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96618(MLS000537230 | N-[[4-[(6-chloranylpyridin-3-yl)met...)
Affinity DataEC50:  1.11E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM68155(MLS001005764 | SMR000384079 | cid_16196355 | nitri...)
Affinity DataEC50:  1.14E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96649(1-(2,6-dichlorophenoxy)-3-(1,2,3,4-tetrahydronapht...)
Affinity DataEC50:  1.17E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96619(4-{[(isobutyrylamino)carbothioyl]amino}-N-(4-metho...)
Affinity DataEC50:  1.90E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96792(1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(3-ethoxyphenyl...)
Affinity DataEC50:  1.94E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96744(2-(4-chlorophenoxy)ethyl-phenethyl-amine;oxalic ac...)
Affinity DataEC50:  2.19E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96835(4-(1-amino-2-phenylmethoxyethyl)-N-(6-methoxy-2-py...)
Affinity DataEC50:  2.22E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96755(7-Methyl-3-[(2-m-tolyl-ethylamino)-methyl]-1H-quin...)
Affinity DataEC50:  2.49E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96745(1,2-bis[(Z)-(4-fluorobenzylidene)amino]guanidine;h...)
Affinity DataEC50:  2.61E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96818(MLS002608065 | N-(2-phenylethoxy)-1-(3-pyridinyl)m...)
Affinity DataEC50: >2.98E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96697(3-anilino-1,2,4-triazin-5(4H)-one | 3-anilino-2H-1...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96622(5-chloranyl-4-[(2Z)-2-[(3-methylphenyl)methylidene...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96776(4-nitro-5-[(E)-2-phenylethenyl]-1H-imidazole | 4-n...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96743(4-methyl-1,2,3,4-tetrahydro-[1]benzofuro[3,2-c]pyr...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96865((2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-(m-anis...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96877((2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-(o-tolu...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96559(2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96851(2-amino-5-isopropyl-N-(2-(thiophen-2-yl)ethyl)thio...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96807(1-[2,5-dimethyl-1-(2-phenylethyl)-3-pyrrolyl]-2-[4...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96885((2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[(3,4-d...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM96828((3E)-3-[1-[2-(4-hydroxyphenyl)ethylamino]ethyliden...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGuanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65923(1-(3-Fluoro-phenyl)-3-pyridin-3-yl-urea | 1-(3-flu...)
Affinity DataEC50: >2.99E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
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