Compile Data Set for Download or QSAR
maximum 50k data
Found 2495 of ic50 for UniProtKB: P07333
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377072(CHEMBL438533)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27912(8-(4-ethylphenyl)-N-methoxy-2-{[4-(1-methylpiperid...)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377072(CHEMBL438533)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321368(4-cyano-N-(4-(1,3-dimethyl-2-oxohexahydropyrimidin...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321373(4-cyano-N-(4-(2-(cyanoimino)-1,3-dimethylhexahydro...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27913(8-(3-ethylphenyl)-N-methoxy-2-{[4-(1-methylpiperid...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27909(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377071(CHEMBL402337)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27915(8-(4,4-dimethylcyclohexyl)-N-methoxy-2-{[4-(1-meth...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27897(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321365(4-cyano-N-(2-cyclohexenyl-4-(1-methyl-2,6-dioxopip...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321367(4-cyano-N-(2-cyclohexenyl-4-(1,3-dimethyl-2-oxohex...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50240209(CHEMBL4068526)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50240227(CHEMBL4084391)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27896(8-(2,3-dihydro-1H-inden-5-yl)-N-ethoxy-2-({4-[2-(4...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27906(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-5-oxo-2-{[...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50579499(CHEMBL4847875)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of wild-type human partial length CSF1R (I564 to S939 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM595657(US11591328, Compound 10)
Affinity DataIC50:  0.550nMAssay Description:CSF1R: The specific operation is as follows: Set the concentration gradient of the test compound and dilute the test compound to the working concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of CSF1R (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM119049(CHEMBL3086320 | US8674100, 20 | US8674100, 69)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50443154(CHEMBL3085973 | US8674100, 147)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233716(5-cyano-N-(4-(4-(2-hydroxyethyl)piperazin-1-yl)-2-...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50393560(CHEMBL2158300 | US8697716, 48)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM595552(US11591328, Compound 1)
Affinity DataIC50:  0.660nMAssay Description:CSF1R: The specific operation is as follows: Set the concentration gradient of the test compound and dilute the test compound to the working concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50355499(CHEMBL1908395 | CHEMBL1908842)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50393562(CHEMBL2158302)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of recombinant CSF1R (unknown origin) using poly (Glu, Tyr)4:1 as substrate measured after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233720(CHEMBL254909 | N-(4-(4-acetylpiperazin-1-yl)-2-(4-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27894(8-(2,3-dihydro-1H-inden-5-yl)-N-(2-hydroxyethyl)-2...)
Affinity DataIC50:  0.700nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233701(5-cyano-furan-2-carboxylic acid [4-(1,1-dioxo-1lam...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27895(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...)
Affinity DataIC50:  0.700nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27910(2-{[4-(3,3-difluoro-1-methylpiperidin-4-yl)phenyl]...)
Affinity DataIC50:  0.700nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50443167(CHEMBL3085977 | US8674100, 76)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50506458(CHEMBL4576115)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant CSF1R using ATP/Ulight-TK peptide incubated for 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM119044(CHEMBL3085833 | US8674100, 62 | US8674100, 63)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27917(4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-methylp...)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233715(5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27917(4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-methylp...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27890(8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50321364(4-cyano-N-(2-(4,4-dimethylcyclohex-1-enyl)-4-(2,6-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human FMS by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27903(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-5-oxo-2-({...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27904(8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27917(4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-methylp...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377060(CHEMBL255443)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50377059(CHEMBL257620)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50443140(CHEMBL3085984 | US8674100, 150)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM119043(CHEMBL3085978 | US8674100, 60 | US9221797, 60)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27911(8-(2,3-dihydro-1H-inden-5-yl)-2-{[3-(1-ethyl-3-hyd...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM27917(4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-methylp...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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