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Compile Data Set for Download or QSAR

Found 545 hits of ec50 for UniProtKB: Q9NR97   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Toll-like receptor 8


(Homo sapiens (Human))
BDBM507044
PNG
(2-Amino-8-(5-chloro-1,4-dihydroquinazolin-2-yl)-N,...)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2c(C)cccc2N1
Show InChI InChI=1S/C26H31N5O/c1-4-11-31(12-5-2)26(32)20-13-18-9-10-19(14-23(18)29-24(27)15-20)25-28-16-21-17(3)7-6-8-22(21)30-25/h6-10,13-14H,4-5,11-12,15-16H2,1-3H3,(H2,27,29)(H,28,30)
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Hoffmann-La Roche Inc.

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US11046671 (2021)

More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254777
PNG
(US9475775, 44 | US9475775, 79 | US9597333, 44)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCC)c1
Show InChI InChI=1S/C25H31N5O3/c1-4-9-30(10-5-2)25(32)19-11-17-7-8-18(12-22(17)29-23(26)13-19)24(31)28-20-14-21(33-6-3)16-27-15-20/h7-8,11-12,14-16H,4-6,9-10,13H2,1-3H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254777
PNG
(US9475775, 44 | US9475775, 79 | US9597333, 44)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCC)c1
Show InChI InChI=1S/C25H31N5O3/c1-4-9-30(10-5-2)25(32)19-11-17-7-8-18(12-22(17)29-23(26)13-19)24(31)28-20-14-21(33-6-3)16-27-15-20/h7-8,11-12,14-16H,4-6,9-10,13H2,1-3H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254734
PNG
(US9475775, 1 | US9597333, 1)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C23H27N5O2/c1-3-10-28(11-4-2)23(30)18-12-16-7-8-17(13-20(16)27-21(24)14-18)22(29)26-19-6-5-9-25-15-19/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,24,27)(H,26,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254735
PNG
(US9475775, 2 | US9597333, 2)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncnc1
Show InChI InChI=1S/C22H26N6O2/c1-3-7-28(8-4-2)22(30)17-9-15-5-6-16(10-19(15)27-20(23)11-17)21(29)26-18-12-24-14-25-13-18/h5-6,9-10,12-14H,3-4,7-8,11H2,1-2H3,(H2,23,27)(H,26,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254747
PNG
(US9475775, 14 | US9597333, 14)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C25H30N4O2/c1-4-11-29(12-5-2)25(31)20-14-18-9-10-19(15-22(18)28-23(26)16-20)24(30)27-21-8-6-7-17(3)13-21/h6-10,13-15H,4-5,11-12,16H2,1-3H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254756
PNG
(US9475775, 23 | US9597333, 23)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cc(C)cc(C)c1
Show InChI InChI=1S/C26H32N4O2/c1-5-9-30(10-6-2)26(32)21-14-19-7-8-20(15-23(19)29-24(27)16-21)25(31)28-22-12-17(3)11-18(4)13-22/h7-8,11-15H,5-6,9-10,16H2,1-4H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254761
PNG
(US9475775, 28 | US9597333, 28)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C25H30N4O2/c1-4-12-29(13-5-2)25(31)20-14-18-8-9-19(15-22(18)28-23(26)16-20)24(30)27-21-10-6-17(3)7-11-21/h6-11,14-15H,4-5,12-13,16H2,1-3H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254762
PNG
(US9475775, 29 | US9597333, 29)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CC)c1
Show InChI InChI=1S/C26H32N4O2/c1-4-12-30(13-5-2)26(32)21-15-19-10-11-20(16-23(19)29-24(27)17-21)25(31)28-22-9-7-8-18(6-3)14-22/h7-11,14-16H,4-6,12-13,17H2,1-3H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254768
PNG
(US9475775, 35 | US9597333, 35)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(OCC)nc1
Show InChI InChI=1S/C25H31N5O3/c1-4-11-30(12-5-2)25(32)19-13-17-7-8-18(14-21(17)29-22(26)15-19)24(31)28-20-9-10-23(27-16-20)33-6-3/h7-10,13-14,16H,4-6,11-12,15H2,1-3H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254734
PNG
(US9475775, 1 | US9597333, 1)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C23H27N5O2/c1-3-10-28(11-4-2)23(30)18-12-16-7-8-17(13-20(16)27-21(24)14-18)22(29)26-19-6-5-9-25-15-19/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,24,27)(H,26,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254735
PNG
(US9475775, 2 | US9597333, 2)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncnc1
Show InChI InChI=1S/C22H26N6O2/c1-3-7-28(8-4-2)22(30)17-9-15-5-6-16(10-19(15)27-20(23)11-17)21(29)26-18-12-24-14-25-13-18/h5-6,9-10,12-14H,3-4,7-8,11H2,1-2H3,(H2,23,27)(H,26,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254747
PNG
(US9475775, 14 | US9597333, 14)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C25H30N4O2/c1-4-11-29(12-5-2)25(31)20-14-18-9-10-19(15-22(18)28-23(26)16-20)24(30)27-21-8-6-7-17(3)13-21/h6-10,13-15H,4-5,11-12,16H2,1-3H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254756
PNG
(US9475775, 23 | US9597333, 23)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cc(C)cc(C)c1
Show InChI InChI=1S/C26H32N4O2/c1-5-9-30(10-6-2)26(32)21-14-19-7-8-20(15-23(19)29-24(27)16-21)25(31)28-22-12-17(3)11-18(4)13-22/h7-8,11-15H,5-6,9-10,16H2,1-4H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254761
PNG
(US9475775, 28 | US9597333, 28)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C25H30N4O2/c1-4-12-29(13-5-2)25(31)20-14-18-8-9-19(15-22(18)28-23(26)16-20)24(30)27-21-10-6-17(3)7-11-21/h6-11,14-15H,4-5,12-13,16H2,1-3H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254762
PNG
(US9475775, 29 | US9597333, 29)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CC)c1
Show InChI InChI=1S/C26H32N4O2/c1-4-12-30(13-5-2)26(32)21-15-19-10-11-20(16-23(19)29-24(27)17-21)25(31)28-22-9-7-8-18(6-3)14-22/h7-11,14-16H,4-6,12-13,17H2,1-3H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254768
PNG
(US9475775, 35 | US9597333, 35)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(OCC)nc1
Show InChI InChI=1S/C25H31N5O3/c1-4-11-30(12-5-2)25(32)19-13-17-7-8-18(14-21(17)29-22(26)15-19)24(31)28-20-9-10-23(27-16-20)33-6-3/h7-10,13-14,16H,4-6,11-12,15H2,1-3H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254773
PNG
(US9475775, 40 | US9597333, 40)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OC)c1
Show InChI InChI=1S/C24H29N5O3/c1-4-8-29(9-5-2)24(31)18-10-16-6-7-17(11-21(16)28-22(25)12-18)23(30)27-19-13-20(32-3)15-26-14-19/h6-7,10-11,13-15H,4-5,8-9,12H2,1-3H3,(H2,25,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254773
PNG
(US9475775, 40 | US9597333, 40)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OC)c1
Show InChI InChI=1S/C24H29N5O3/c1-4-8-29(9-5-2)24(31)18-10-16-6-7-17(11-21(16)28-22(25)12-18)23(30)27-19-13-20(32-3)15-26-14-19/h6-7,10-11,13-15H,4-5,8-9,12H2,1-3H3,(H2,25,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM507050
PNG
(2-Amino-8-(6-methoxy-1,4-dihydroquinazolin-2-yl)-N...)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2cc(OC)ccc2N1
Show InChI InChI=1S/C26H31N5O2/c1-4-10-31(11-5-2)26(32)19-12-17-6-7-18(14-23(17)29-24(27)15-19)25-28-16-20-13-21(33-3)8-9-22(20)30-25/h6-9,12-14H,4-5,10-11,15-16H2,1-3H3,(H2,27,29)(H,28,30)
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Hoffmann-La Roche Inc.

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US11046671 (2021)

More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254788
PNG
(US9475775, 55 | US9597333, 55)
Show SMILES CCCN(CC(C)C)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C26H32N4O2/c1-5-11-30(16-17(2)3)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-8-6-7-18(4)12-22/h6-10,12-14,17H,5,11,15-16H2,1-4H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254786
PNG
(US9475775, 53 | US9597333, 53)
Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C26H30N4O2/c1-3-11-30(16-18-7-8-18)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-6-4-5-17(2)12-22/h4-6,9-10,12-14,18H,3,7-8,11,15-16H2,1-2H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254788
PNG
(US9475775, 55 | US9597333, 55)
Show SMILES CCCN(CC(C)C)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C26H32N4O2/c1-5-11-30(16-17(2)3)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-8-6-7-18(4)12-22/h6-10,12-14,17H,5,11,15-16H2,1-4H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM301880
PNG
(2-Amino-N4-(cyclopropylmethyl)-N8-(5-ethoxy-3-pyri...)
Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCC)c1
Show InChI InChI=1S/C26H31N5O3/c1-3-9-31(16-17-5-6-17)26(33)20-10-18-7-8-19(11-23(18)30-24(27)12-20)25(32)29-21-13-22(34-4-2)15-28-14-21/h7-8,10-11,13-15,17H,3-6,9,12,16H2,1-2H3,(H2,27,30)(H,29,32)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM380607
PNG
(2-Amino-8-[3-[3-(hydroxymethyl)azetidin-1-yl]sulfo...)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cccc(c1)S(=O)(=O)N1CC(CO)C1
Show InChI InChI=1S/C27H34N4O4S/c1-3-10-30(11-4-2)27(33)23-12-22-9-8-21(14-25(22)29-26(28)15-23)20-6-5-7-24(13-20)36(34,35)31-16-19(17-31)18-32/h5-9,12-14,19,32H,3-4,10-11,15-18H2,1-2H3,(H2,28,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9890124 (2018)


BindingDB Entry DOI: 10.7270/Q2BK1FP9
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254777
PNG
(US9475775, 44 | US9475775, 79 | US9597333, 44)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(OCC)c1
Show InChI InChI=1S/C25H31N5O3/c1-4-9-30(10-5-2)25(32)19-11-17-7-8-18(12-22(17)29-23(26)13-19)24(31)28-20-14-21(33-6-3)16-27-15-20/h7-8,11-12,14-16H,4-6,9-10,13H2,1-3H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254743
PNG
(US9475775, 10 | US9597333, 10)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C24H27ClN4O2/c1-3-11-29(12-4-2)24(31)18-13-16-5-6-17(14-21(16)28-22(26)15-18)23(30)27-20-9-7-19(25)8-10-20/h5-10,13-14H,3-4,11-12,15H2,1-2H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254748
PNG
(US9475775, 15 | US9597333, 15)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(c1)C(=O)N1CCCC1
Show InChI InChI=1S/C29H35N5O3/c1-3-12-33(13-4-2)29(37)23-16-20-10-11-21(18-25(20)32-26(30)19-23)27(35)31-24-9-7-8-22(17-24)28(36)34-14-5-6-15-34/h7-11,16-18H,3-6,12-15,19H2,1-2H3,(H2,30,32)(H,31,35)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254751
PNG
(US9475775, 18 | US9597333, 18)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(C)c1
Show InChI InChI=1S/C24H29N5O2/c1-4-8-29(9-5-2)24(31)19-11-17-6-7-18(12-21(17)28-22(25)13-19)23(30)27-20-10-16(3)14-26-15-20/h6-7,10-12,14-15H,4-5,8-9,13H2,1-3H3,(H2,25,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254759
PNG
(US9475775, 26 | US9597333, 26)
Show SMILES CCCN(CCCO)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C25H30N4O3/c1-3-10-29(11-5-12-30)25(32)20-14-18-8-9-19(15-22(18)28-23(26)16-20)24(31)27-21-7-4-6-17(2)13-21/h4,6-9,13-15,30H,3,5,10-12,16H2,1-2H3,(H2,26,28)(H,27,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254763
PNG
(US9475775, 30 | US9597333, 30)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OC)c1
Show InChI InChI=1S/C25H30N4O3/c1-4-11-29(12-5-2)25(31)19-13-17-9-10-18(14-22(17)28-23(26)15-19)24(30)27-20-7-6-8-21(16-20)32-3/h6-10,13-14,16H,4-5,11-12,15H2,1-3H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254765
PNG
(US9475775, 32 | US9597333, 32)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C24H27ClN4O2/c1-3-10-29(11-4-2)24(31)18-12-16-8-9-17(13-21(16)28-22(26)14-18)23(30)27-20-7-5-6-19(25)15-20/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254766
PNG
(US9475775, 33 | US9597333, 33)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(CN)c1
Show InChI InChI=1S/C24H30N6O2/c1-3-7-30(8-4-2)24(32)19-10-17-5-6-18(11-21(17)29-22(26)12-19)23(31)28-20-9-16(13-25)14-27-15-20/h5-6,9-11,14-15H,3-4,7-8,12-13,25H2,1-2H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254767
PNG
(US9475775, 34 | US9597333, 34)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccnnc1
Show InChI InChI=1S/C22H26N6O2/c1-3-9-28(10-4-2)22(30)17-11-15-5-6-16(12-19(15)27-20(23)13-17)21(29)26-18-7-8-24-25-14-18/h5-8,11-12,14H,3-4,9-10,13H2,1-2H3,(H2,23,27)(H,24,26,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254743
PNG
(US9475775, 10 | US9597333, 10)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C24H27ClN4O2/c1-3-11-29(12-4-2)24(31)18-13-16-5-6-17(14-21(16)28-22(26)15-18)23(30)27-20-9-7-19(25)8-10-20/h5-10,13-14H,3-4,11-12,15H2,1-2H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254748
PNG
(US9475775, 15 | US9597333, 15)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(c1)C(=O)N1CCCC1
Show InChI InChI=1S/C29H35N5O3/c1-3-12-33(13-4-2)29(37)23-16-20-10-11-21(18-25(20)32-26(30)19-23)27(35)31-24-9-7-8-22(17-24)28(36)34-14-5-6-15-34/h7-11,16-18H,3-6,12-15,19H2,1-2H3,(H2,30,32)(H,31,35)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254751
PNG
(US9475775, 18 | US9597333, 18)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(C)c1
Show InChI InChI=1S/C24H29N5O2/c1-4-8-29(9-5-2)24(31)19-11-17-6-7-18(12-21(17)28-22(25)13-19)23(30)27-20-10-16(3)14-26-15-20/h6-7,10-12,14-15H,4-5,8-9,13H2,1-3H3,(H2,25,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254759
PNG
(US9475775, 26 | US9597333, 26)
Show SMILES CCCN(CCCO)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C25H30N4O3/c1-3-10-29(11-5-12-30)25(32)20-14-18-8-9-19(15-22(18)28-23(26)16-20)24(31)27-21-7-4-6-17(2)13-21/h4,6-9,13-15,30H,3,5,10-12,16H2,1-2H3,(H2,26,28)(H,27,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254763
PNG
(US9475775, 30 | US9597333, 30)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(OC)c1
Show InChI InChI=1S/C25H30N4O3/c1-4-11-29(12-5-2)25(31)19-13-17-9-10-18(14-22(17)28-23(26)15-19)24(30)27-20-7-6-8-21(16-20)32-3/h6-10,13-14,16H,4-5,11-12,15H2,1-3H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254765
PNG
(US9475775, 32 | US9597333, 32)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C24H27ClN4O2/c1-3-10-29(11-4-2)24(31)18-12-16-8-9-17(13-21(16)28-22(26)14-18)23(30)27-20-7-5-6-19(25)15-20/h5-9,12-13,15H,3-4,10-11,14H2,1-2H3,(H2,26,28)(H,27,30)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254766
PNG
(US9475775, 33 | US9597333, 33)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cncc(CN)c1
Show InChI InChI=1S/C24H30N6O2/c1-3-7-30(8-4-2)24(32)19-10-17-5-6-18(11-21(17)29-22(26)12-19)23(31)28-20-9-16(13-25)14-27-15-20/h5-6,9-11,14-15H,3-4,7-8,12-13,25H2,1-2H3,(H2,26,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254767
PNG
(US9475775, 34 | US9597333, 34)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1ccnnc1
Show InChI InChI=1S/C22H26N6O2/c1-3-9-28(10-4-2)22(30)17-11-15-5-6-16(12-19(15)27-20(23)13-17)21(29)26-18-7-8-24-25-14-18/h5-8,11-12,14H,3-4,9-10,13H2,1-2H3,(H2,23,27)(H,24,26,29)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254784
PNG
(US9475775, 51 | US9597333, 51)
Show SMILES CCCN(CCC(F)(F)F)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C25H27F3N4O2/c1-3-10-32(11-9-25(26,27)28)24(34)19-13-17-7-8-18(14-21(17)31-22(29)15-19)23(33)30-20-6-4-5-16(2)12-20/h4-8,12-14H,3,9-11,15H2,1-2H3,(H2,29,31)(H,30,33)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254786
PNG
(US9475775, 53 | US9597333, 53)
Show SMILES CCCN(CC1CC1)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C26H30N4O2/c1-3-11-30(16-18-7-8-18)26(32)21-13-19-9-10-20(14-23(19)29-24(27)15-21)25(31)28-22-6-4-5-17(2)12-22/h4-6,9-10,12-14,18H,3,7-8,11,15-16H2,1-2H3,(H2,27,29)(H,28,31)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254784
PNG
(US9475775, 51 | US9597333, 51)
Show SMILES CCCN(CCC(F)(F)F)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C25H27F3N4O2/c1-3-10-32(11-9-25(26,27)28)24(34)19-13-17-7-8-18(14-21(17)31-22(29)15-19)23(33)30-20-6-4-5-16(2)12-20/h4-8,12-14H,3,9-11,15H2,1-2H3,(H2,29,31)(H,30,33)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM507035
PNG
(2-Amino-8-(1,4-dihydroquinazolin-2-yl)-N,N-dipropy...)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2ccccc2N1
Show InChI InChI=1S/C25H29N5O/c1-3-11-30(12-4-2)25(31)20-13-17-9-10-18(14-22(17)28-23(26)15-20)24-27-16-19-7-5-6-8-21(19)29-24/h5-10,13-14H,3-4,11-12,15-16H2,1-2H3,(H2,26,28)(H,27,29)
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Hoffmann-La Roche Inc.

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US11046671 (2021)

More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254792
PNG
(US9475775, 59 | US9597333, 59)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCCN)c1
Show InChI InChI=1S/C27H35N5O2/c1-3-13-32(14-4-2)27(34)22-16-20-10-11-21(17-24(20)31-25(29)18-22)26(33)30-23-9-5-7-19(15-23)8-6-12-28/h5,7,9-11,15-17H,3-4,6,8,12-14,18,28H2,1-2H3,(H2,29,31)(H,30,33)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9475775 (2016)


BindingDB Entry DOI: 10.7270/Q2QC02D4
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM507049
PNG
(2-Amino-8-(5-fluoro-1,4-dihydroquinazolin-2-yl)-N,...)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2c(F)cccc2N1
Show InChI InChI=1S/C25H28FN5O/c1-3-10-31(11-4-2)25(32)18-12-16-8-9-17(13-22(16)29-23(27)14-18)24-28-15-19-20(26)6-5-7-21(19)30-24/h5-9,12-13H,3-4,10-11,14-15H2,1-2H3,(H2,27,29)(H,28,30)
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Hoffmann-La Roche Inc.

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US11046671 (2021)

More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254750
PNG
(US9475775, 17 | US9475775, 54 | US9597333, 54)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCN)c1
Show InChI InChI=1S/C26H33N5O2/c1-3-12-31(13-4-2)26(33)21-15-19-8-9-20(16-23(19)30-24(28)17-21)25(32)29-22-7-5-6-18(14-22)10-11-27/h5-9,14-16H,3-4,10-13,17,27H2,1-2H3,(H2,28,30)(H,29,32)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
Toll-like receptor 8


(Homo sapiens (Human))
BDBM254792
PNG
(US9475775, 59 | US9597333, 59)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C(=O)Nc1cccc(CCCN)c1
Show InChI InChI=1S/C27H35N5O2/c1-3-13-32(14-4-2)27(34)22-16-20-10-11-21(17-24(20)31-25(29)18-22)26(33)30-23-9-5-7-19(15-23)8-6-12-28/h5,7,9-11,15-17H,3-4,6,8,12-14,18,28H2,1-2H3,(H2,29,31)(H,30,33)
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Hoffmann-La Roche Inc

US Patent


Assay Description
For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...


US Patent US9597333 (2017)


BindingDB Entry DOI: 10.7270/Q2474CXF
More data for this
Ligand-Target Pair
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