TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.460nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.623nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.623nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.623nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.623nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.996nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.996nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 0.996nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK7 (unknown origin) incubated for 180 mins by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Competitive inhibition of human CDK7 in presence of ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human CDK7 incubated for 180 mins by LanthaScreen Eu Kinase binding assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of full-length recombinant human His-tagged CDK7 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDk7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK7 (unknown origin) expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin) in presence of ATP incubated for 1 hr by FRET based envision plate reader methodMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of full-length recombinant human His-tagged CDK7 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK7/cyclin H by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:The IMAP technology is based on the high affinity binding of phosphate by immobilized metal coordination complexes on nanoparticles. This IMAP bindin...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 11.3nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 11.4nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 11.4nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-m...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 13.9nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK7 (unknown origin) by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: <15nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
The People'S Hospital Of Xinjiang Uyghur Autonomous Region
Curated by ChEMBL
Affinity DataIC50: 15.7nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Selected compounds disclosed herein were tested in kinase assays by Nanosyn (Santa Clara, Calif.) to determine their inhibitory effect on these CDKs....More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Tianjin University Of Science And Technology
Curated by ChEMBL
Tianjin University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 16.7nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair