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Found 22 of ic50 for UniProtKB: P12276
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50362887(AVICULARIN)
Affinity DataIC50:  6.15E+3nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50318454(CHEMBL123040 | Diallyl trisulfide | diallyltrisulf...)
Affinity DataIC50:  8.37E+3nMpH: 7.0 T: 2°CAssay Description:FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50318454(CHEMBL123040 | Diallyl trisulfide | diallyltrisulf...)
Affinity DataIC50:  8.37E+3nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM240798(Ginkgolic acid C17:2 (2))
Affinity DataIC50:  9.20E+3nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50259930(6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-he...)
Affinity DataIC50:  1.05E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50349517(CHEMBL1808693)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of chicken FAS by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  1.30E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50394659(CHEMBL2165410)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50:  1.71E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50394660(CHEMBL2165409)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50153015((-)-Epicatechin-3-gallate | (-)-epicatechin 3-O-ga...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of chicken liver FASN after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of chicken liver FASNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of chicken liver FASN using acetyl-CoA, malonyl-CoA and NADPH as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  5.93E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  6.25E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50153015((-)-Epicatechin-3-gallate | (-)-epicatechin 3-O-ga...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50394663(CHEMBL2165267)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50318453(3-Allyldisulfanyl-propene | CHEMBL366603 | Diallyl...)
Affinity DataIC50:  1.45E+5nMpH: 7.0 T: 2°CAssay Description:FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM233038(Dimethyl disulfide)
Affinity DataIC50:  2.21E+6nMpH: 7.0 T: 2°CAssay Description:FAS activity was determined by monitoring the decrease in absorbence at 340 nm resulting from the oxidation of NADPH using an Amersham Pharmacia Ultr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed