Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 7841
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222054((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-bromophenyl)acryloy...)
Affinity DataKi:  0.245nM ΔG°:  -54.9kJ/mole IC50:  0.352nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222051((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-chlorophenyl)acrylo...)
Affinity DataKi:  0.258nM ΔG°:  -54.7kJ/mole IC50:  0.373nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222046((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-methoxyphenyl)acryl...)
Affinity DataKi:  0.277nM ΔG°:  -54.5kJ/mole IC50:  0.356nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222050((3aR,4S,7R,7aS)-2-(4-((E)-3-(o-tolyl)acryloyl)phen...)
Affinity DataKi:  0.302nM ΔG°:  -54.3kJ/mole IC50:  0.353nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222047((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-methoxyphenyl)acryl...)
Affinity DataKi:  0.337nM ΔG°:  -54.1kJ/mole IC50:  0.435nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222055((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-bromophenyl)acryloy...)
Affinity DataKi:  0.343nM ΔG°:  -54.0kJ/mole IC50:  0.382nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  0.343nM ΔG°:  -54.0kJ/mole IC50:  0.485nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222052((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-chlorophenyl)acrylo...)
Affinity DataKi:  0.361nM ΔG°:  -53.9kJ/mole IC50:  0.419nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222053((3aR,4S,7R,7aS)-2-(4-((E)-3-(2-chlorophenyl)acrylo...)
Affinity DataKi:  0.377nM ΔG°:  -53.8kJ/mole IC50:  0.444nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222056((3aR,4S,7R,7aS)-2-(4-((E)-3-(2-bromophenyl)acryloy...)
Affinity DataKi:  0.379nM ΔG°:  -53.8kJ/mole IC50:  0.415nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222057((3aR,4S,7R,7aS)-2-(4-((E)-3-(furan-2-yl)acryloyl)p...)
Affinity DataKi:  0.390nM ΔG°:  -53.7kJ/mole IC50:  0.555nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222048((3aR,4S,7R,7aS)-2-(4-((E)-3-(p-tolyl)acryloyl)phen...)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/mole IC50:  0.406nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222049((3aR,4S,7R,7aS)-2-(4-((E)-3-(m-tolyl)acryloyl)phen...)
Affinity DataKi:  0.404nM ΔG°:  -53.6kJ/mole IC50:  0.449nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222056((3aR,4S,7R,7aS)-2-(4-((E)-3-(2-bromophenyl)acryloy...)
Affinity DataKi:  0.405nM ΔG°:  -53.6kJ/mole IC50:  0.573nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222058((3aR,4S,7R,7aS)-2-(4-((E)-3-(thiophen-2-yl)acryloy...)
Affinity DataKi:  0.412nM ΔG°:  -53.6kJ/mole IC50:  0.488nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222054((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-bromophenyl)acryloy...)
Affinity DataKi:  0.442nM ΔG°:  -53.4kJ/mole IC50:  0.466nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222047((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-methoxyphenyl)acryl...)
Affinity DataKi:  0.469nM ΔG°:  -53.2kJ/mole IC50:  0.606nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222051((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-chlorophenyl)acrylo...)
Affinity DataKi:  0.475nM ΔG°:  -53.2kJ/mole IC50:  0.506nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222059((3aR,4S,7R,7aS)-2-(4-((E)-3-(pyridin-4-yl)acryloyl...)
Affinity DataKi:  0.490nM ΔG°:  -53.1kJ/mole IC50:  0.551nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222055((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-bromophenyl)acryloy...)
Affinity DataKi:  0.501nM ΔG°:  -53.1kJ/mole IC50:  0.597nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222046((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-methoxyphenyl)acryl...)
Affinity DataKi:  0.513nM ΔG°:  -53.0kJ/mole IC50:  0.639nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222052((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-chlorophenyl)acrylo...)
Affinity DataKi:  0.518nM ΔG°:  -53.0kJ/mole IC50:  0.619nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222049((3aR,4S,7R,7aS)-2-(4-((E)-3-(m-tolyl)acryloyl)phen...)
Affinity DataKi:  0.523nM ΔG°:  -53.0kJ/mole IC50:  0.579nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222050((3aR,4S,7R,7aS)-2-(4-((E)-3-(o-tolyl)acryloyl)phen...)
Affinity DataKi:  0.529nM ΔG°:  -52.9kJ/mole IC50:  0.537nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222059((3aR,4S,7R,7aS)-2-(4-((E)-3-(pyridin-4-yl)acryloyl...)
Affinity DataKi:  0.549nM ΔG°:  -52.9kJ/mole IC50:  0.611nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222057((3aR,4S,7R,7aS)-2-(4-((E)-3-(furan-2-yl)acryloyl)p...)
Affinity DataKi:  0.595nM ΔG°:  -52.7kJ/mole IC50:  0.655nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222053((3aR,4S,7R,7aS)-2-(4-((E)-3-(2-chlorophenyl)acrylo...)
Affinity DataKi:  0.603nM ΔG°:  -52.6kJ/mole IC50:  0.650nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222048((3aR,4S,7R,7aS)-2-(4-((E)-3-(p-tolyl)acryloyl)phen...)
Affinity DataKi:  0.605nM ΔG°:  -52.6kJ/mole IC50:  0.597nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM222058((3aR,4S,7R,7aS)-2-(4-((E)-3-(thiophen-2-yl)acryloy...)
Affinity DataKi:  0.636nM ΔG°:  -52.5kJ/mole IC50:  0.711nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Cumhuriyet University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  0.747nM ΔG°:  -52.1kJ/mole IC50:  0.996nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair