Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50000269
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003780(4-(3-Pyridin-3-yl-propyl)-8-(toluene-4-sulfonylami...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003792(8-(4-Fluoro-benzenesulfonylamino)-4-(3-pyridin-3-y...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003784(8-(4-Chloro-benzenesulfonylamino)-4-[3-(4-methyl-p...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003803(8-(Naphthalene-2-sulfonylamino)-4-(3-pyridin-3-yl-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003801(4-(3-Pyridin-3-yl-propyl)-8-(4-trifluoromethyl-ben...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003781(CHEMBL341686 | [5-(4-Chloro-benzenesulfonylamino)-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003796(8-(4-Chloro-benzenesulfonylamino)-4-[3-(1-oxy-pyri...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003799(8-(4-Chloro-benzenesulfonylamino)-2-methyl-4-(3-py...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003798(8-(4-Chloro-benzenesulfonylamino)-4-(3-imidazol-1-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003800(8-(4-Methoxy-benzenesulfonylamino)-4-(3-pyridin-3-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003797(8-(4-Chloro-benzenesulfonylamino)-4-[2-(pyridin-3-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003789(8-(4-Methanesulfonyl-benzenesulfonylamino)-4-(3-py...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003794(8-(4-Azido-benzenesulfonylamino)-4-(3-pyridin-3-yl...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003787(4-Chloro-N-{8-pyridin-3-yl-5-[2-(5H-tetrazol-5-yl)...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003790(CHEMBL136880 | Potassium; 8-(4-chloro-benzenesulfo...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003804(7-(4-Chloro-benzenesulfonylamino)-3-(3-pyridin-3-y...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003793(8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003791(CHEMBL343535 | [5-(4-Chloro-benzenesulfonylamino)-...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003776(8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003783(8-(4-Chloro-benzenesulfonylamino)-2,2-dimethyl-4-(...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003786(8-(4-Chloro-benzenesulfonylamino)-4-(2-imidazol-1-...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003788(8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003782(4-Chloro-N-[5-(3-hydroxy-propyl)-8-pyridin-3-yl-oc...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003802(6-(4-Chloro-benzenesulfonylamino)-2-(3-pyridin-3-y...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50003785(CHEMBL137187 | N-[5-(4-Chloro-benzenesulfonylamino...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed